Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABBR2 | O75899 | 2/20 | 0.46 |
| ▸ | GABBR1 | Q9UBS5 | 2/20 | 0.46 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.46 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.43 |
| ▸ | GLRB | P48167 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 4/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.39 |
| ▸ | CA4 | P22748 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | MIF | P14174 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MPI | P34949 | 1/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10807980 | 1.00 | GABBR2 (0.46) | GABBR2GABBR1TNFRSF1AGLRA3GLRB | |
| SCHEMBL28419451 | 0.87 | GABBR2 (0.43) | GABBR2GABBR1TNFRSF1AGLRA3GLRB | |
| SCHEMBL11301999 | 0.84 | GABBR2 (0.41) | GABBR2GABBR1TNFRSF1AGLRA3GLRB | |
| SCHEMBL10717937 | 0.83 | GABBR2 (0.40) | GABBR2GABBR1TNFRSF1AGLRA3GLRB | |
| SCHEMBL699096 | 0.82 | GABBR2 (0.40) | GABBR2GABBR1TNFRSF1AGLRA3GLRB | |
| SCHEMBL1615105 | 0.81 | PTGS2 (0.50) | GABBR2GABBR1TNFRSF1AGLRA3GLRB | |
| SCHEMBL689068 | 0.81 | PTGS2 (0.50) | GABBR2GABBR1TNFRSF1AGLRA3GLRB | |
| SCHEMBL696524 | 0.80 | GABBR2 (0.38) | GABBR2GABBR1TNFRSF1AGLRA3GLRB | |
| SCHEMBL4816185 | 0.78 | GAA (0.47) | GAAKMT2ATYRESR1ESR2 | |
| SCHEMBL698507 | 0.78 | GABBR2 (0.36) | GABBR2GABBR1TNFRSF1AGLRA3GLRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0818526-B1 | Stabilizers for the prevention of gum formation in gasoline | CIBA SC HOLDING AG (CH) | 2003-02-12 | — | — | EP | claimed |
| US-RE32334-E | Molding resins | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1987-01-20 | — | — | US | disclosed |