Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | F2 | P00734 | 1/20 | 0.58 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | ELANE | P08246 | 4/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.54 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.54 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.54 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6937804 | 1.00 | ALDH1A1 (0.67) | ALDH1A1SRD5A2LMNAF2ATM | |
| SCHEMBL8717537 | 0.93 | LMNA (0.67) | ALDH1A1SRD5A2LMNAF2TDP1 | |
| SCHEMBL19666759 | 0.92 | MAPT (0.62) | ALDH1A1SRD5A2LMNAF2ATM | |
| Hydrogen Peroxide SCHEMBL27952375 | 0.90 | LMNA (0.70) | ALDH1A1LMNAF2TDP1L3MBTL1 | |
| SCHEMBL52413 | 0.90 | LMNA (0.70) | ALDH1A1LMNAF2TDP1L3MBTL1 | |
| Benzene SCHEMBL27793442 | 0.90 | LMNA (0.70) | ALDH1A1LMNAF2TDP1L3MBTL1 | |
| SCHEMBL27616691 | 0.90 | L3MBTL1 (0.69) | ALDH1A1SRD5A2LMNAF2ATM | |
| SCHEMBL1534569 | 0.87 | LMNA (0.67) | ALDH1A1LMNAF2TDP1L3MBTL1 | |
| SCHEMBL7050451 | 0.87 | LMNA (0.67) | ALDH1A1LMNAF2TDP1L3MBTL1 | |
| Phosphine SCHEMBL9591710 | 0.87 | LMNA (0.67) | ALDH1A1LMNAF2TDP1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0972776-B1 | A phosphine sulfide, a manufacturing process therefor and a use thereof | MITSUI CHEMICALS INC (JP) | 2003-04-23 | — | — | EP | disclosed |
| US-6153794-A | Phosphine sulfide, a manufacturing process therefor and use thereof | MITSUI CHEMICALS, INC. (JP) | 2000-11-28 | — | — | US | disclosed |
| CN-1262276-A | Phosphine sulfide preparing process and use thereof | MITSUI CHEMICALS INC (JP) | 2000-08-09 | — | — | CN | disclosed |
| EP-0972776-A1 | A phosphine sulfide, a manufacturing process therefor and a use thereof | Mitsui Chemicals, Inc. (JP) | 2000-01-19 | — | — | EP | disclosed |
| WO-1999032428-A2 | SYNTHESIS OF DIAMINES | INTERNATIONAL CENTRE FOR GENETIC ENGINEERING AND BIOTECHNOLOGY (IT) | 1999-07-01 | — | — | WO | disclosed |