Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SLC16A3 | O15427 | 5/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA6 | P23280 | 1/20 | 0.32 |
| ▸ | CA5A | P35218 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5043210 | 0.79 | ALDH1A1 (0.45) | ALDH1A1POLBHPGDSLC16A3LMNA | |
| SCHEMBL6761344 | 0.77 | ADRA2C (0.45) | ALDH1A1TDP1POLBL3MBTL1GAA | |
| SCHEMBL6938190 | 0.77 | F7 (0.44) | MAPT | |
| SCHEMBL23766361 | 0.76 | ALDH1A1 (0.42) | TLR8ALDH1A1TDP1USP2HPGD | |
| Hydrochloric Acid SCHEMBL27904214 | 0.76 | ADRA2C (0.44) | ALDH1A1TDP1POLBL3MBTL1GAA | |
| SCHEMBL29573161 | 0.76 | POLB (0.44) | TLR8ALDH1A1TDP1POLBL3MBTL1 | |
| SCHEMBL7446162 | 0.76 | POLB (0.44) | TLR8ALDH1A1TDP1POLBL3MBTL1 | |
| SCHEMBL19285031 | 0.76 | TLR8 (0.53) | TLR8ALDH1A1TDP1L3MBTL1USP2 | |
| SCHEMBL15187595 | 0.76 | ALDH1A1 (0.38) | ALDH1A1TDP1POLBL3MBTL1GAA | |
| SCHEMBL6939595 | 0.74 | HTR2A (0.48) | ALDH1A1L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1272456-A1 | HYDRAZIDE AND ALKOXYAMIDE ANGIOGENESIS INHIBITORS | Abbott Laboratories (US) | 2003-01-08 | — | — | EP | disclosed |
| WO-2001079157-A1 | HYDRAZIDE AND ALKOXYAMIDE ANGIOGENESIS INHIBITORS | ABBOTT LABORATORIES (US) | 2001-10-25 | — | — | WO | disclosed |