Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6719348 | 0.85 | SLC9A1 (0.57) | SLC9A1 | |
| SCHEMBL1763798 | 0.84 | CA12 (0.51) | SLC9A1LMNATSHRCA12CA1 | |
| SCHEMBL6938080 | 0.81 | SLC9A1 (0.45) | SLC9A1 | |
| SCHEMBL1763859 | 0.80 | SLC9A1 (0.42) | SLC9A1LMNATSHRCA1CA2 | |
| SCHEMBL7670684 | 0.77 | GPR27 (0.38) | TSHR | |
| SCHEMBL8536954 | 0.77 | SLC9A1 (0.49) | SLC9A1CA12CA1CA2CA9 | |
| SCHEMBL8663752 | 0.77 | SLC9A1 (0.42) | SLC9A1 | |
| SCHEMBL8663733 | 0.77 | SLC9A1 (0.42) | SLC9A1 | |
| SCHEMBL8542825 | 0.77 | SLC9A1 (0.49) | SLC9A1 | |
| SCHEMBL7800866 | 0.76 | SLC9A1 (0.78) | SLC9A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0758644-B1 | Sulfonyl- or sulfinyl-benzoyl-guanidine derivatives | MERCK PATENT GMBH (DE) | 2003-10-15 | — | — | EP | disclosed |
| CN-1071743-C | Sulfuryl or sulfinyl benzoyl guanidine derivative | MERCK PATENT GMBH (DE) | 2001-09-26 | — | — | CN | disclosed |
| EP-0760365-B1 | Alkenyl-benzoylguanidines | MERCK PATENT GMBH (DE) | 2001-01-03 | — | — | EP | disclosed |
| CN-1055919-C | Arylbenzoylguanidin | MERCK PATENT GMBH (DE) | 2000-08-30 | — | — | CN | disclosed |
| EP-0699660-B1 | Arylbenzoylguanidines | MERCK PATENT GMBH (DE) | 1998-10-28 | — | — | EP | disclosed |
| US-5807896-A | Arylbenzoylguanidines | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTING (DE) | 1998-09-15 | — | — | US | disclosed |
| US-5744641-A | Sulfonyl- or sulfinylbenzoylguanidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-04-28 | — | — | US | disclosed |
| US-5731351-A | Alkenyl-benzoylguanidine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-03-24 | — | — | US | disclosed |
| CN-1148590-A | Sulfuryl or sulfinyl benzoyl guanidine derivative | MERCK PATENT GMBH (DE) | 1997-04-30 | — | — | CN | disclosed |
| EP-0760365-A2 | Alkenyl-benzoylguanidines | MERCK PATENT GmbH (DE) | 1997-03-05 | — | — | EP | disclosed |
| EP-0758644-A1 | Sulfonyl- or sulfinyl-benzoyl-guanidine derivatives | MERCK PATENT GmbH (DE) | 1997-02-19 | — | — | EP | disclosed |
| EP-0699660-A2 | Arylbenzoylguanidines | MERCK PATENT GmbH (DE) | 1996-03-06 | — | — | EP | disclosed |
| CN-1117962-A | Arylbenzoylguanidin | MERCK PATENT GMBH (DE) | 1996-03-06 | — | — | CN | disclosed |