Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.52 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.52 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.52 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.43 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.43 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 2-Naphthaldehyde SCHEMBL6544637 | 0.84 | RELA (0.55) | GRIK1GRIK2GRIK3RELACYP3A4 | |
| 2-Naphthaldehyde SCHEMBL9383019 | 0.84 | RECQL (0.43) | GRIK1GRIK2GRIK3RAB9A | |
| 2-Naphthaldehyde SCHEMBL28251938 | 0.83 | ALDH1A1 (0.50) | RELACYP3A4KDM4EALDH1A1L3MBTL1 | |
| 2-Naphthaldehyde SCHEMBL28866061 | 0.82 | RELA (0.61) | RELAKDM4EALDH1A1L3MBTL1SMN1; SMN2 | |
| Benzaldehyde SCHEMBL11621909 | 0.81 | ALDH1A1 (0.58) | GRIK1GRIK2ALDH1A1KMT2A | |
| Benzaldehyde SCHEMBL441456 | 0.81 | ALDH1A1 (0.58) | GRIK1GRIK2ALDH1A1KMT2A | |
| Naphthalene SCHEMBL699807 | 0.80 | TAAR1 (0.46) | EPHX1KDM4EALDH1A1LMNA | |
| Naphthalene SCHEMBL699808 | 0.80 | TAAR1 (0.46) | EPHX1KDM4EALDH1A1LMNA | |
| 2-Naphthaldehyde SCHEMBL51340 | 0.80 | RELA (0.58) | RELAKDM4EALDH1A1L3MBTL1SMN1; SMN2 | |
| 2-Naphthaldehyde SCHEMBL30229844 | 0.80 | RELA (0.58) | RELAKDM4EALDH1A1L3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5470830-A | Motilin-like polypeptides that inhibit gastrointestinal motor activity | OHMEDA PHARMACEUTICAL PRODUCTS DIVISION INC. (US) | 1995-11-28 | — | — | US | claimed |
| WO-1992010510-A1 | DITHIOLANO- AND DITHIANOGLYCIN-CONTAINING RENIN-INHIBITING PEPTIDES, PROCESS FOR PRODUCING THE SAME AND THEIR USE IN MEDICAMENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1992-06-25 | — | — | WO | claimed |
| US-20030018438-A1 | Binding compounds and methods for identifying binding compounds | IWA, LLC | 2003-01-23 | — | — | US | disclosed |
| EP-1268520-A2 | RECEPTOR-BINDING COMPOUNDS AND METHODS FOR IDENTIFYING THEM | Consensus Pharmaceuticals, Inc. (US) | 2003-01-02 | — | — | EP | disclosed |
| WO-2002057313-A2 | RECEPTOR-BINDING COMPOUNDS AND METHODS FOR IDENTIFYING THEM | CONSENSUS PHARMACEUTICALS, INC. (US) | 2002-07-25 | — | — | WO | disclosed |
| WO-2001070768-A2 | RECEPTOR-BINDING COMPOUNDS AND METHOD FOR IDENTIFYING THEM | CONSENSUS PHARMACEUTICALS, INC. (US) | 2001-09-27 | — | — | WO | disclosed |
| WO-1992010510-A1 | DITHIOLANO- AND DITHIANOGLYCIN-CONTAINING RENIN-INHIBITING PEPTIDES, PROCESS FOR PRODUCING THE SAME AND THEIR USE IN MEDICAMENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1992-06-25 | — | — | WO | disclosed |