Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | RARA | P10276 | 1/20 | 0.31 |
| ▸ | RARB | P10826 | 1/20 | 0.31 |
| ▸ | RARG | P13631 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6940536 | 0.77 | CYP11B1 (0.37) | RXRARXRBCYP19A1CYP11B1CYP11B2 | |
| SCHEMBL6940199 | 0.77 | RXRB (0.33) | RXRARXRB | |
| SCHEMBL6940332 | 0.74 | CYP11B1 (0.35) | RXRARXRBCYP19A1CYP11B1CYP11B2 | |
| SCHEMBL29606082 | 0.73 | HSP90AA1 (0.34) | RXRARXRBRARBRARG | |
| SCHEMBL21776799 | 0.72 | RARB (0.40) | RXRARXRBRARARARBRARG | |
| SCHEMBL29873435 | 0.72 | RARB (0.40) | RXRARXRBRARARARBRARG | |
| SCHEMBL6939426 | 0.71 | RXRB (0.39) | RXRARXRBCYP19A1CYP11B1CYP11B2 | |
| SCHEMBL6942040 | 0.71 | CYP11B1 (0.36) | CYP19A1CYP11B1CYP11B2 | |
| SCHEMBL6280690 | 0.71 | CYP11B1 (0.47) | RXRARXRBCYP19A1CYP11B1CYP11B2 | |
| SCHEMBL29897870 | 0.71 | CYP11B1 (0.47) | RXRARXRBCYP19A1CYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6479424-B1 | FOR PRODUCING OLEFIN POLYMERS AND ESPECIALLY ELASTOMERIC PROPYLENE POLYMERS | BP CORPORATION NORTH AMERICA INC. | 2002-11-12 | — | — | US | claimed |
| EP-1157047-B1 | LIGANDS AND CATALYSTS FOR PRODUCING ELASTOMERIC PROPYLENE POLYMERS | BP CORP NORTH AMERICA INC (US) | 2003-04-23 | — | — | EP | disclosed |
| US-6479424-B1 | FOR PRODUCING OLEFIN POLYMERS AND ESPECIALLY ELASTOMERIC PROPYLENE POLYMERS | BP CORPORATION NORTH AMERICA INC. | 2002-11-12 | — | — | US | disclosed |
| EP-1157047-A1 | LIGANDS AND CATALYSTS FOR PRODUCING ELASTOMERIC PROPYLENE POLYMERS | BP Corporation North America Inc. (US) | 2001-11-28 | — | — | EP | disclosed |
| WO-2000035975-A1 | LIGANDS AND CATALYSTS FOR PRODUCING ELASTOMERIC PROPYLENE POLYMERS | BP CORPORATION NORTH AMERICA INC. (US) | 2000-06-22 | — | — | WO | disclosed |