SCHEMBL6939426

SCHEMBL6939426

CC(C)(C)c1cc(C2=Cc3cc(-c4ccccc4)ccc3C2)cc(C(C)(C)C)c1

nearest known ligand 0.39

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
RXRB P28702 9/20 0.39
RXRA P19793 8/20 0.39
RXRG P48443 4/20 0.39
CYP11B1 P15538 2/20 0.39
CYP11B2 P19099 2/20 0.39
CYP19A1 P11511 1/20 0.39
KIF11 P52732 1/20 0.36
IP6K1 Q92551 1/20 0.34
IP6K3 Q96PC2 1/20 0.34
TDP2 O95551 1/20 0.33
HSD17B2 P37059 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6940536 0.83 CYP11B1 (0.37) RXRBRXRARXRGCYP11B1CYP11B2
SCHEMBL29897870 0.83 CYP11B1 (0.47) RXRBRXRARXRGCYP11B1CYP11B2
SCHEMBL6280690 0.83 CYP11B1 (0.47) RXRBRXRARXRGCYP11B1CYP11B2
Hydrochloric Acid SCHEMBL28814933 0.80 CYP11B2 (0.46) CYP11B1CYP11B2CYP19A1IP6K1IP6K3
SCHEMBL6940332 0.79 CYP11B1 (0.35) RXRBRXRARXRGCYP11B1CYP11B2
SCHEMBL28814932 0.77 CYP11B1 (0.41) CYP11B1CYP11B2CYP19A1IP6K1IP6K3
SCHEMBL6942040 0.77 CYP11B1 (0.36) CYP11B1CYP11B2CYP19A1
SCHEMBL29672902 0.77 PTGS2 (0.42) CYP11B1CYP11B2CYP19A1IP6K1IP6K3
SCHEMBL7178824 0.77 PTGS2 (0.42) CYP11B1CYP11B2CYP19A1IP6K1IP6K3
SCHEMBL19432718 0.76 MMP3 (0.48) CYP11B1CYP11B2CYP19A1TDP2HSD17B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1157047-B1 LIGANDS AND CATALYSTS FOR PRODUCING ELASTOMERIC PROPYLENE POLYMERS BP CORP NORTH AMERICA INC (US) 2003-04-23 EP disclosed
US-6479424-B1 FOR PRODUCING OLEFIN POLYMERS AND ESPECIALLY ELASTOMERIC PROPYLENE POLYMERS BP CORPORATION NORTH AMERICA INC. 2002-11-12 US disclosed
EP-1157047-A1 LIGANDS AND CATALYSTS FOR PRODUCING ELASTOMERIC PROPYLENE POLYMERS BP Corporation North America Inc. (US) 2001-11-28 EP disclosed
WO-2000035975-A1 LIGANDS AND CATALYSTS FOR PRODUCING ELASTOMERIC PROPYLENE POLYMERS BP CORPORATION NORTH AMERICA INC. (US) 2000-06-22 WO disclosed