Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 3/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 5/20 | 0.32 |
| ▸ | RXRA | P19793 | 4/20 | 0.32 |
| ▸ | RXRG | P48443 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6280690 | 0.83 | CYP11B1 (0.47) | CYP11B1CYP11B2CYP19A1RXRBRXRA | |
| SCHEMBL29897870 | 0.83 | CYP11B1 (0.47) | CYP11B1CYP11B2CYP19A1RXRBRXRA | |
| SCHEMBL6940536 | 0.80 | CYP11B1 (0.37) | CYP11B1CYP11B2CYP19A1KDM4EGAA | |
| SCHEMBL6940199 | 0.80 | RXRB (0.33) | KDM4EGAAMAPTRXRBRXRA | |
| SCHEMBL6939426 | 0.79 | RXRB (0.39) | CYP11B1CYP11B2CYP19A1RXRBRXRA | |
| SCHEMBL6942183 | 0.76 | S1PR1 (0.33) | KDM4EGAAMAPTS1PR1S1PR3 | |
| SCHEMBL7090598 | 0.74 | CYP11B2 (0.50) | CYP11B1CYP11B2CYP19A1KDM4EMAPT | |
| SCHEMBL6942040 | 0.74 | CYP11B1 (0.36) | CYP11B1CYP11B2CYP19A1KDM4EGAA | |
| SCHEMBL6938203 | 0.74 | RXRA (0.33) | CYP11B1CYP11B2CYP19A1RXRBRXRA | |
| SCHEMBL21776765 | 0.72 | PTGS2 (0.41) | CYP11B1CYP11B2CYP19A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1157047-B1 | LIGANDS AND CATALYSTS FOR PRODUCING ELASTOMERIC PROPYLENE POLYMERS | BP CORP NORTH AMERICA INC (US) | 2003-04-23 | — | — | EP | disclosed |
| US-6479424-B1 | FOR PRODUCING OLEFIN POLYMERS AND ESPECIALLY ELASTOMERIC PROPYLENE POLYMERS | BP CORPORATION NORTH AMERICA INC. | 2002-11-12 | — | — | US | disclosed |
| EP-1157047-A1 | LIGANDS AND CATALYSTS FOR PRODUCING ELASTOMERIC PROPYLENE POLYMERS | BP Corporation North America Inc. (US) | 2001-11-28 | — | — | EP | disclosed |
| WO-2000035975-A1 | LIGANDS AND CATALYSTS FOR PRODUCING ELASTOMERIC PROPYLENE POLYMERS | BP CORPORATION NORTH AMERICA INC. (US) | 2000-06-22 | — | — | WO | disclosed |