Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 1/20 | 0.52 |
| ▸ | PPARA | Q07869 | 14/20 | 0.49 |
| ▸ | PPARG | P37231 | 14/20 | 0.49 |
| ▸ | PPARD | Q03181 | 10/20 | 0.49 |
| ▸ | ELANE | P08246 | 2/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6933186 | 0.92 | PPARG (0.48) | LTB4RPPARAPPARGPPARD | |
| SCHEMBL7074267 | 0.87 | PPARA (0.61) | LTB4RPPARAPPARGPPARD | |
| SCHEMBL6938370 | 0.87 | PPARG (0.58) | LTB4RPPARAPPARGPPARDSRD5A2 | |
| SCHEMBL6934429 | 0.84 | PPARA (0.58) | LTB4RPPARAPPARGPPARD | |
| SCHEMBL6932996 | 0.83 | PPARG (0.43) | LTB4RPPARAPPARGPPARD | |
| SCHEMBL6933000 | 0.83 | PPARG (0.43) | LTB4RPPARAPPARGPPARD | |
| SCHEMBL6933761 | 0.83 | LTB4R (0.51) | LTB4RPPARAPPARGPPARDELANE | |
| SCHEMBL6935714 | 0.81 | PPARG (0.61) | LTB4RPPARAPPARGPPARD | |
| SCHEMBL6934303 | 0.80 | THRA (0.47) | LTB4RPPARAPPARGPPARD | |
| SCHEMBL6939543 | 0.77 | PPARG (0.58) | LTB4RPPARAPPARGPPARDSRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888278-B1 | ANTIDIABETIC AGENTS | MERCK & CO INC (US) | 2003-07-23 | — | — | EP | claimed |
| EP-0888278-A4 | ANTIDIABETIC AGENTS | MERCK & CO INC (US) | 1999-06-30 | — | — | EP | claimed |
| EP-0888278-A1 | ANTIDIABETIC AGENTS | Merck & Co., Inc. (US) | 1999-01-07 | — | — | EP | claimed |
| WO-1997028115-A1 | ANTIDIABETIC AGENTS | MERCK & CO., INC. (US) | 1997-08-07 | — | — | WO | claimed |
| EP-0888278-B1 | ANTIDIABETIC AGENTS | MERCK & CO INC (US) | 2003-07-23 | — | — | EP | disclosed |
| EP-0888278-A4 | ANTIDIABETIC AGENTS | MERCK & CO INC (US) | 1999-06-30 | — | — | EP | disclosed |
| EP-0888278-A1 | ANTIDIABETIC AGENTS | Merck & Co., Inc. (US) | 1999-01-07 | — | — | EP | disclosed |
| WO-1997028115-A1 | ANTIDIABETIC AGENTS | MERCK & CO., INC. (US) | 1997-08-07 | — | — | WO | disclosed |