Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 12/20 | 0.58 |
| ▸ | PPARA | Q07869 | 11/20 | 0.58 |
| ▸ | PPARD | Q03181 | 11/20 | 0.58 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.54 |
| ▸ | FOS | P01100 | 1/20 | 0.49 |
| ▸ | JUN | P05412 | 1/20 | 0.49 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.49 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6936861 | 0.89 | PPARA (0.59) | PPARGPPARAPPARDLTB4RFOS | |
| SCHEMBL6935714 | 0.88 | PPARG (0.61) | PPARGPPARAPPARDLTB4RFOS | |
| SCHEMBL6936456 | 0.88 | PPARG (0.49) | PPARGPPARAPPARDLTB4RLTB4R2 | |
| SCHEMBL6938259 | 0.87 | LTB4R (0.52) | PPARGPPARAPPARDLTB4RSRD5A2 | |
| SCHEMBL6933761 | 0.86 | LTB4R (0.51) | PPARGPPARAPPARDLTB4RSRD5A2 | |
| SCHEMBL6936579 | 0.85 | PPARG (0.63) | PPARGPPARAPPARD | |
| SCHEMBL6934325 | 0.81 | PPARG (0.59) | PPARGPPARAPPARDLTB4RFOS | |
| SCHEMBL7074267 | 0.80 | PPARA (0.61) | PPARGPPARAPPARDLTB4RLTB4R2 | |
| SCHEMBL6938382 | 0.80 | PPARG (0.64) | PPARGPPARAPPARDLTB4RFOS | |
| SCHEMBL6934429 | 0.79 | PPARA (0.58) | PPARGPPARAPPARDLTB4RLTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0888278-B1 | ANTIDIABETIC AGENTS | MERCK & CO INC (US) | 2003-07-23 | — | — | EP | claimed |
| EP-0888278-A4 | ANTIDIABETIC AGENTS | MERCK & CO INC (US) | 1999-06-30 | — | — | EP | claimed |
| EP-0888278-A1 | ANTIDIABETIC AGENTS | Merck & Co., Inc. (US) | 1999-01-07 | — | — | EP | claimed |
| WO-1997028115-A1 | ANTIDIABETIC AGENTS | MERCK & CO., INC. (US) | 1997-08-07 | — | — | WO | claimed |
| EP-0888278-B1 | ANTIDIABETIC AGENTS | MERCK & CO INC (US) | 2003-07-23 | — | — | EP | disclosed |
| EP-0888278-A4 | ANTIDIABETIC AGENTS | MERCK & CO INC (US) | 1999-06-30 | — | — | EP | disclosed |
| EP-0888278-A1 | ANTIDIABETIC AGENTS | Merck & Co., Inc. (US) | 1999-01-07 | — | — | EP | disclosed |
| WO-1997028115-A1 | ANTIDIABETIC AGENTS | MERCK & CO., INC. (US) | 1997-08-07 | — | — | WO | disclosed |