Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 4/20 | 0.66 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.47 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.47 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2386152 | 0.93 | ALDH1A1 (0.68) | KEAP1NFE2L2ALDH1A1L3MBTL1KMT2A | |
| SCHEMBL6938020 | 0.86 | NPC1 (0.53) | KEAP1NFE2L2ALDH1A1L3MBTL1KMT2A | |
| SCHEMBL2879389 | 0.86 | MAPT (0.65) | KEAP1NFE2L2ALDH1A1L3MBTL1KMT2A | |
| SCHEMBL30393962 | 0.86 | MAPT (0.65) | KEAP1NFE2L2ALDH1A1L3MBTL1KMT2A | |
| SCHEMBL6937072 | 0.85 | NPC1 (0.71) | KEAP1NFE2L2ALDH1A1L3MBTL1NPC1 | |
| SCHEMBL31670390 | 0.82 | MAPT (0.68) | KEAP1NFE2L2ALDH1A1KMT2AMEN1 | |
| SCHEMBL13800968 | 0.82 | MAPT (0.68) | KEAP1NFE2L2ALDH1A1KMT2AMEN1 | |
| SCHEMBL600330 | 0.81 | ALDH1A1 (0.85) | KEAP1NFE2L2ALDH1A1L3MBTL1KMT2A | |
| SCHEMBL31276140 | 0.81 | ALDH1A1 (0.85) | KEAP1NFE2L2ALDH1A1L3MBTL1KMT2A | |
| SCHEMBL30808237 | 0.81 | ALDH1A1 (0.85) | KEAP1NFE2L2ALDH1A1L3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1190441-C | Phosphine sulfide preparing process and use thereof | MITSUI CHEMICALS INC (JP) | 2005-02-23 | — | — | CN | disclosed |
| EP-0972776-B1 | A phosphine sulfide, a manufacturing process therefor and a use thereof | MITSUI CHEMICALS INC (JP) | 2003-04-23 | — | — | EP | disclosed |
| US-6153794-A | Phosphine sulfide, a manufacturing process therefor and use thereof | MITSUI CHEMICALS, INC. (JP) | 2000-11-28 | — | — | US | disclosed |
| CN-1262276-A | Phosphine sulfide preparing process and use thereof | MITSUI CHEMICALS INC (JP) | 2000-08-09 | — | — | CN | disclosed |
| EP-0972776-A1 | A phosphine sulfide, a manufacturing process therefor and a use thereof | Mitsui Chemicals, Inc. (JP) | 2000-01-19 | — | — | EP | disclosed |