Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.51 |
| ▸ | PTK2B | Q14289 | 2/20 | 0.51 |
| ▸ | NCOA1 | Q15788 | 2/20 | 0.51 |
| ▸ | NCOA3 | Q9Y6Q9 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6937072 | 0.86 | NPC1 (0.71) | NPC1MAPTHTTALDH1A1LMNA | |
| SCHEMBL6938522 | 0.86 | KEAP1 (0.66) | NPC1MAPTMEN1KMT2AMAPK10 | |
| SCHEMBL20695793 | 0.80 | MAPT (0.53) | NPC1MAPTMEN1KMT2AMAPK10 | |
| SCHEMBL21776920 | 0.79 | MYC (0.58) | NPC1MAPTMEN1KMT2AMAPK10 | |
| SCHEMBL2386152 | 0.79 | ALDH1A1 (0.68) | NPC1MAPTMEN1KMT2ANPSR1 | |
| SCHEMBL3616574 | 0.78 | ALDH1A1 (0.74) | NPC1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3616572 | 0.78 | MAPT (0.52) | NPC1MAPTMEN1KMT2AMAPK10 | |
| SCHEMBL31278212 | 0.78 | ALDH1A1 (0.74) | NPC1MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2402121 | 0.77 | ALDH1A1 (0.50) | NPC1MAPTMEN1KMT2AMAPK10 | |
| SCHEMBL3605801 | 0.77 | MAPT (0.50) | NPC1MAPTMEN1KMT2AMAPK10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0972776-B1 | A phosphine sulfide, a manufacturing process therefor and a use thereof | MITSUI CHEMICALS INC (JP) | 2003-04-23 | — | — | EP | disclosed |
| US-6153794-A | Phosphine sulfide, a manufacturing process therefor and use thereof | MITSUI CHEMICALS, INC. (JP) | 2000-11-28 | — | — | US | disclosed |
| CN-1262276-A | Phosphine sulfide preparing process and use thereof | MITSUI CHEMICALS INC (JP) | 2000-08-09 | — | — | CN | disclosed |
| EP-0972776-A1 | A phosphine sulfide, a manufacturing process therefor and a use thereof | Mitsui Chemicals, Inc. (JP) | 2000-01-19 | — | — | EP | disclosed |
| US-4764566-A | HIGH STRENGTH | ALLIED-SIGNAL INC. (US) | 1988-08-16 | — | — | US | disclosed |