Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.68 |
| ▸ | MAPT | P10636 | 3/20 | 0.68 |
| ▸ | LMNA | P02545 | 3/20 | 0.68 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2386152 | 0.93 | ALDH1A1 (0.68) | NPC1ALDH1A1MAPTLMNAL3MBTL1 | |
| SCHEMBL6938020 | 0.86 | NPC1 (0.53) | NPC1ALDH1A1MAPTLMNAL3MBTL1 | |
| SCHEMBL21840821 | 0.86 | NPC1 (0.71) | NPC1ALDH1A1MAPTLMNAL3MBTL1 | |
| SCHEMBL6938522 | 0.85 | KEAP1 (0.66) | NPC1ALDH1A1MAPTLMNAL3MBTL1 | |
| SCHEMBL7825548 | 0.83 | NPC1 (0.52) | NPC1ALDH1A1MAPTLMNAL3MBTL1 | |
| SCHEMBL581124 | 0.81 | ALDH1A1 (1.00) | NPC1ALDH1A1MAPTLMNAL3MBTL1 | |
| SCHEMBL4343114 | 0.80 | NPC1 (0.56) | NPC1ALDH1A1MAPTLMNAL3MBTL1 | |
| SCHEMBL7829487 | 0.79 | KEAP1 (0.73) | NPC1ALDH1A1MAPTLMNAL3MBTL1 | |
| SCHEMBL5729760 | 0.79 | ALDH1A1 (0.70) | NPC1ALDH1A1MAPTLMNAL3MBTL1 | |
| SCHEMBL8279098 | 0.79 | ALDH1A1 (0.70) | NPC1ALDH1A1MAPTLMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1190441-C | Phosphine sulfide preparing process and use thereof | MITSUI CHEMICALS INC (JP) | 2005-02-23 | — | — | CN | disclosed |
| EP-0972776-B1 | A phosphine sulfide, a manufacturing process therefor and a use thereof | MITSUI CHEMICALS INC (JP) | 2003-04-23 | — | — | EP | disclosed |
| US-6153794-A | Phosphine sulfide, a manufacturing process therefor and use thereof | MITSUI CHEMICALS, INC. (JP) | 2000-11-28 | — | — | US | disclosed |
| CN-1262276-A | Phosphine sulfide preparing process and use thereof | MITSUI CHEMICALS INC (JP) | 2000-08-09 | — | — | CN | disclosed |
| EP-0972776-A1 | A phosphine sulfide, a manufacturing process therefor and a use thereof | Mitsui Chemicals, Inc. (JP) | 2000-01-19 | — | — | EP | disclosed |