Known targets — ChEMBL curated mechanism
rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.53 |
| ▸ | PPARG | P37231 | 7/20 | 0.53 |
| ▸ | PPARD | Q03181 | 7/20 | 0.53 |
| ▸ | PPARA | Q07869 | 7/20 | 0.53 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.53 |
| ▸ | TSHR | P16473 | 4/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | TLR2 | O60603 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | FABP4 | P15090 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.53 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | ESR1 | P03372 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | PDE4A | P27815 | 1/20 | 0.53 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adipic Acid SCHEMBL7993766 | 0.92 | VCAM1 (0.55) | TSHRALDH1A1TDP1KMT2AMEN1 | |
| Adipic Acid SCHEMBL28216161 | 0.92 | VCAM1 (0.55) | TSHRALDH1A1TDP1KMT2AMEN1 | |
| Stearic Acid SCHEMBL1592198 | 0.87 | GAA (0.57) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL4384130 | 0.83 | VCAM1 (0.49) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL4398044 | 0.83 | VCAM1 (0.49) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL27383361 | 0.83 | VCAM1 (0.49) | GPR84PPARGPPARDPPARAHDAC11 | |
| Stearic Acid SCHEMBL30966112 | 0.83 | VCAM1 (0.46) | GPR84PPARGPPARDPPARAHDAC11 | |
| Octane SCHEMBL8468280 | 0.83 | GAA (0.59) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL9174972 | 0.83 | GAA (0.59) | GPR84PPARGPPARDPPARAHDAC11 | |
| Palmitic Acid SCHEMBL11546991 | 0.83 | GPR84 (0.71) | GPR84PPARGPPARDPPARAHDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116268692-A | Knitted textile and vamp and manufacturing method thereof | 耐克创新有限合伙公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-113576109-B | Knitted textile and shoe upper and manufacturing method thereof | 耐克创新有限合伙公司 | 2023-03-28 | — | — | CN | disclosed |
| CN-115413862-A | Knitted textile and shoe upper and manufacturing method thereof | 耐克创新有限合伙公司 | 2022-12-02 | — | — | CN | disclosed |
| CN-115413861-A | Knitted textile and shoe upper and manufacturing method thereof | 耐克创新有限合伙公司 | 2022-12-02 | — | — | CN | disclosed |
| CN-113576109-A | Knitted textile and shoe upper and manufacturing method thereof | 耐克创新有限合伙公司 | 2021-11-02 | — | — | CN | disclosed |
| CN-108056532-B | Knitted textile and shoe upper and manufacturing method thereof | 耐克创新有限合伙公司 | 2021-06-25 | — | — | CN | disclosed |
| CN-207898025-U | Combination vamp and outsole for footwear product | 耐克创新有限合伙公司 | 2018-09-25 | — | — | CN | disclosed |
| CN-108056532-A | Knitted textile and shoe upper and manufacturing method thereof | 耐克创新有限合伙公司 | 2018-05-22 | — | — | CN | disclosed |
| EP-0742254-B1 | Resin having reduced rate of sulfur acceptance | CLARIANT GMBH (DE) | 2003-09-03 | — | — | EP | disclosed |
| CN-1082066-C | Synergistic stabilizer mixture | CIBA SC HOLDING AG (CH) | 2002-04-03 | — | — | CN | disclosed |
| CN-1079809-C | Synergistic stabilizer mixture | CIBA SC HOLDING AG (CH) | 2002-02-27 | — | — | CN | disclosed |
| CN-1074017-C | Method for increasing molecular weight of polycondensates | CIBA GEIGY AG (CH) | 2001-10-31 | — | — | CN | disclosed |
| US-5852159-A | Plastic with reduced sulfur uptake rate | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-12-22 | — | — | US | disclosed |
| CN-1162325-A | Method for increasing molecular weight of polycondensates | CIBA GEIGY AG (CH) | 1997-10-15 | — | — | CN | disclosed |
| CN-1137541-A | Synergistic stabilizer mixture | CIBA GEIGY AG (CH) | 1996-12-11 | — | — | CN | disclosed |
| CN-1136048-A | Synergistic stabilizer mixture | CIBA GEIGY AG (CH) | 1996-11-20 | — | — | CN | disclosed |
| EP-0742254-A2 | Resin having reduced rate of sulfur acceptance | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-11-13 | — | — | EP | disclosed |
| EP-0705836-A1 | Polyalkylpiperidine compounds | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-04-10 | — | — | EP | disclosed |
| CN-1114653-A | Oligomeric hals phophites and hals phosphonites as stabilisers | CIBA GEIGY AG (CH) | 1996-01-10 | — | — | CN | disclosed |