Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 5/20 | 0.55 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.48 |
| ▸ | GLRB | P48167 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | TYR | P14679 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.44 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adipic Acid SCHEMBL7993766 | 1.00 | VCAM1 (0.55) | VCAM1GLRA3GLRBCA2CA1 | |
| Stearic Acid SCHEMBL6938564 | 0.92 | GPR84 (0.53) | VCAM1ALDH1A1TDP1KMT2AMEN1 | |
| Propionic Acid SCHEMBL1535102 | 0.85 | GLRA3 (0.52) | VCAM1GLRA3GLRBCA2CA1 | |
| SCHEMBL1278399 | 0.84 | GAA (0.56) | VCAM1GLRA3GLRBALDH1A1SMN1; SMN2 | |
| SCHEMBL23293040 | 0.83 | PTGS2 (0.64) | VCAM1GLRA3GLRBALOX5PTGS1 | |
| SCHEMBL11739838 | 0.83 | GAA (0.55) | VCAM1ALDH1A1GAALMNARECQL | |
| SCHEMBL9175258 | 0.83 | GAA (0.55) | VCAM1GLRA3GLRBALDH1A1SMN1; SMN2 | |
| SCHEMBL39476 | 0.83 | GAA (0.55) | VCAM1ALDH1A1GAALMNARECQL | |
| SCHEMBL28432360 | 0.83 | GAA (0.55) | VCAM1ALDH1A1GAALMNARECQL | |
| SCHEMBL11725011 | 0.83 | GAA (0.55) | VCAM1ALDH1A1GAALMNARECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-207898025-U | Combination vamp and outsole for footwear product | 耐克创新有限合伙公司 | 2018-09-25 | — | — | CN | disclosed |
| CN-108056532-A | Knitted textile and shoe upper and manufacturing method thereof | 耐克创新有限合伙公司 | 2018-05-22 | — | — | CN | disclosed |