SCHEMBL6938622

SCHEMBL6938622

Cc1c(CCO)sc[n+]1CC(=O)NCCc1c(Cl)cccc1Cl

nearest known ligand 0.41

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TKT P29401 15/20 0.41
TRPV1 Q8NER1 1/20 0.35
MITF O75030 1/20 0.35
RAD52 P43351 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bromide SCHEMBL3851471 0.99 TKT (0.40) TKTMITFRAD52
SCHEMBL6933080 0.78 TKT (0.55) TKT
Hydrochloric Acid SCHEMBL3845516 0.77 TKT (0.56) TKT
SCHEMBL3965750 0.72 SMN1; SMN2 (0.47) TKT
SCHEMBL3844576 0.71 ALDH1A1 (0.40) TRPV1
Bromide SCHEMBL3846006 0.71 TKT (0.41) TKTMITFRAD52
SCHEMBL6935005 0.70 MITF (0.55) TKTMITFRAD52
SCHEMBL6936407 0.70 TKT (0.46) TKT
Hydrochloric Acid SCHEMBL3849477 0.70 TKT (0.51) TKT
SCHEMBL5015373 0.70 TKT (0.51) TKT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0808163-B1 USE OF THIAZOLIUM COMPOUNDS FOR PREVENTING AND REVERSING THE FORMATION OF ADVANCED GLYCOSYLATION ENDPRODUCTS ALTEON INC (US) 2003-07-23 EP claimed