SCHEMBL6938663

SCHEMBL6938663

COCCSCC(=O)c1ccc(F)cc1F

nearest known ligand 0.51

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CES2 O00748 2/20 0.45
CES1 P23141 2/20 0.45
ACKR3 P25106 5/20 0.40
GAA P10253 1/20 0.37
USP2 O75604 1/20 0.37
HSD17B10 Q99714 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
ALDH1A1 P00352 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7803890 0.86 CES2 (0.42) CES2CES1ACKR3ALDH1A1
SCHEMBL7802614 0.86 CES2 (0.42) CES2CES1ACKR3GAAL3MBTL1
SCHEMBL7806398 0.82 CES2 (0.50) CES2CES1ACKR3L3MBTL1ALDH1A1
SCHEMBL6944178 0.80 CES2 (0.52) CES2CES1ACKR3L3MBTL1ALDH1A1
SCHEMBL7803902 0.79 GRM5 (0.42) CES2CES1GAAALDH1A1
SCHEMBL3907572 0.78 ACKR3 (0.49) CES2CES1ACKR3GAAHSD17B10
SCHEMBL31711605 0.77 CES2 (0.55) CES2CES1ACKR3GAAL3MBTL1
SCHEMBL7804378 0.77 CES2 (0.55) CES2CES1ACKR3L3MBTL1ALDH1A1
SCHEMBL6945739 0.75 CES2 (0.42) CES2CES1GAAL3MBTL1ALDH1A1
SCHEMBL29145581 0.74 CES2 (0.47) CES2CES1ACKR3L3MBTL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0899265-B1 Triazole derivatives and their use as antimycotic agents SSP CO LTD (JP) 2003-01-29 EP disclosed
EP-0814079-B1 Triazole derivative or salt thereof SS PHARMACEUTICAL CO (JP) 2001-03-28 EP disclosed
US-6063945-A FUNGICIDES SS PHARMACEUTICAL CO., LTD. (JP) 2000-05-16 US disclosed
US-6008239-A FUNGICIDES FOR THE PREVENTION AND TREATMENT OF MAMMALIAN MYCOTIC INFECTIONS SSP CO., LTD. (JP) 1999-12-28 US disclosed
US-5939448-A ANTIMYCOTIC AGENT SS PHARMACEUTICAL CO., LTD. (JP) 1999-08-17 US disclosed
EP-0899265-A1 Triazole derivatives and their use as antimycotic agents SSP Co., Ltd. (JP) 1999-03-03 EP disclosed
EP-0814079-A1 Triazole derivative or salt thereof SS PHARMACEUTICAL CO., LTD. (JP) 1997-12-29 EP disclosed