Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.55 |
| ▸ | CES1 | P23141 | 3/20 | 0.55 |
| ▸ | ACKR3 | P25106 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6944178 | 0.83 | CES2 (0.52) | CES2CES1ACKR3ALDH1A1L3MBTL1 | |
| SCHEMBL9722911 | 0.80 | IKBKB (0.38) | CES2CES1ACKR3ALDH1A1MEN1 | |
| SCHEMBL29145578 | 0.80 | CES2 (0.49) | CES2CES1ACKR3L3MBTL1KMT2A | |
| SCHEMBL13959406 | 0.79 | CES2 (0.61) | CES2CES1ACKR3L3MBTL1 | |
| SCHEMBL29746067 | 0.79 | CES2 (0.61) | CES2CES1ACKR3L3MBTL1 | |
| SCHEMBL196379 | 0.79 | CES2 (0.61) | CES2CES1ACKR3L3MBTL1 | |
| SCHEMBL3765789 | 0.78 | CES2 (0.50) | CES2CES1ACKR3ALDH1A1L3MBTL1 | |
| SCHEMBL7806398 | 0.78 | CES2 (0.50) | CES2CES1ACKR3ALDH1A1L3MBTL1 | |
| SCHEMBL8584 | 0.77 | CES2 (0.63) | CES2CES1ACKR3L3MBTL1 | |
| SCHEMBL7886376 | 0.77 | CES2 (0.49) | CES2CES1ACKR3L3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0780380-B1 | Triazole derivatives with antimycotic action and intermediates | SS PHARMACEUTICAL CO (JP) | 2001-06-13 | — | — | EP | disclosed |
| US-6002028-A | FUNGICIDES | SS PHARMACEUTICAL CO., LTD. (JP) | 1999-12-14 | — | — | US | disclosed |
| US-5986144-A | Triazole derivative, preparation process thereof and pharmaceutical comprising the same as an effective ingredient | SS PHARMACEUTICAL CO., LTD. (JP) | 1999-11-16 | — | — | US | disclosed |
| US-5945438-A | ANTIMYCOTIC AGENT | SS PHARMACEUTICAL CO., LTD. (JP) | 1999-08-31 | — | — | US | disclosed |
| EP-0780380-A1 | Triazole derivatives with antimycotic action and intermediates | SS PHARMACEUTICAL CO., LTD. (JP) | 1997-06-25 | — | — | EP | disclosed |