Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.52 |
| ▸ | CES1 | P23141 | 3/20 | 0.52 |
| ▸ | ACKR3 | P25106 | 5/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7804378 | 0.83 | CES2 (0.55) | CES2CES1ACKR3L3MBTL1ALDH1A1 | |
| SCHEMBL29145581 | 0.83 | CES2 (0.47) | CES2CES1ACKR3L3MBTL1ALDH1A1 | |
| SCHEMBL7806398 | 0.82 | CES2 (0.50) | CES2CES1ACKR3L3MBTL1ALDH1A1 | |
| SCHEMBL10481312 | 0.81 | ALDH1A1 (0.38) | CES2CES1ACKR3ALDH1A1 | |
| SCHEMBL7803890 | 0.81 | CES2 (0.42) | CES2CES1ACKR3ALDH1A1 | |
| SCHEMBL196379 | 0.80 | CES2 (0.61) | CES2CES1ACKR3L3MBTL1KCNH2 | |
| SCHEMBL29746067 | 0.80 | CES2 (0.61) | CES2CES1ACKR3L3MBTL1KCNH2 | |
| SCHEMBL6938663 | 0.80 | CES2 (0.45) | CES2CES1ACKR3L3MBTL1ALDH1A1 | |
| SCHEMBL7802614 | 0.78 | CES2 (0.42) | CES2CES1ACKR3L3MBTL1ALDH1A1 | |
| SCHEMBL29145578 | 0.78 | CES2 (0.49) | CES2CES1ACKR3L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0927719-B1 | Triazole derivative or salt thereof, preparation process thereof as well as pharmaceutical containing said compound | SSP CO LTD (JP) | 2003-07-23 | — | — | EP | disclosed |
| US-6204415-B1 | 2,2-DIFLUORO-2-ETHYLTHIOACETOPHENONE DERIVATIVES OF GIVEN FORMULA WHICH HAVE USE AS INTERMEDIATES TO ANTIMYCOTIC AGENTS | SSP CO., LTD. (JP) | 2001-03-20 | — | — | US | disclosed |
| US-6194592-B1 | AS ANTIMYCOTIC AGENT | SSP CO., LTD. (JP) | 2001-02-27 | — | — | US | disclosed |
| US-6083968-A | A FUNGICIDE; 1,1-DIFLUORO-1-ETHYL THIENYL OR ETHYL THIENYL OXIDES-2-(2,4-SUBSTITUTED PHENYL)-3-(1H-1,2,4-TRIA ZOL-1-YL)-2-OXY OR HYDROXY COMPOUND | SSP CO., LTD. (JP) | 2000-07-04 | — | — | US | disclosed |
| EP-0927719-A1 | Triazole derivative or salt thereof, preparation process thereof as well as pharmaceutical containing said compound | SSP Co., Ltd. (JP) | 1999-07-07 | — | — | EP | disclosed |