Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.61 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.54 |
| ▸ | TNKS | O95271 | 1/20 | 0.51 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.51 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.51 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.51 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.51 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.51 |
| ▸ | KMO | O15229 | 1/20 | 0.51 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.50 |
| ▸ | FEN1 | P39748 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6938778 | 0.89 | AKR1C3 (0.72) | AKR1C3HDAC8TNKSPARP15PARP14 | |
| SCHEMBL6938784 | 0.87 | AKR1C3 (0.70) | AKR1C3HDAC8TNKSPARP15PARP14 | |
| SCHEMBL28299518 | 0.86 | L3MBTL1 (0.50) | AKR1C3PKMRAB9AL3MBTL1CES2 | |
| SCHEMBL8974791 | 0.84 | AKR1C3 (0.49) | AKR1C3HDAC8ERCC5FEN1KDM4E | |
| SCHEMBL27516805 | 0.82 | AKR1C3 (0.64) | AKR1C3HDAC8TNKSPARP15PARP14 | |
| SCHEMBL68858 | 0.79 | AKR1C3 (0.92) | AKR1C3HDAC8TNKSPARP15PARP14 | |
| SCHEMBL30307454 | 0.79 | AKR1C3 (0.92) | AKR1C3HDAC8TNKSPARP15PARP14 | |
| SCHEMBL30449599 | 0.79 | AKR1C3 (0.92) | AKR1C3HDAC8TNKSPARP15PARP14 | |
| SCHEMBL9187797 | 0.79 | AKR1C3 (0.58) | AKR1C3HDAC8TNKSPARP15PARP14 | |
| SCHEMBL5323530 | 0.78 | PARP10 (0.60) | AKR1C3PARP10ERCC5FEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5300543-A | Recyclable thermoplastics foam of high glass temperature | BAYER AKTIENGESELLSCHAFT (DE) | 1994-04-05 | — | — | US | disclosed |