SCHEMBL6938820

SCHEMBL6938820

BrC1CC1.CC(CO)NC(=O)O

nearest known ligand 0.33

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.33
CYP3A4 P08684 2/20 0.32
TSHR P16473 1/20 0.32
CYP2D6 P10635 1/20 0.31
CYP2C19 P33261 1/20 0.31
CNR2 P34972 2/20 0.31
KCNK3 O14649 1/20 0.31
ALDH1A1 P00352 1/20 0.31
THRB P10828 1/20 0.31
BLM P54132 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
CNR1 P21554 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1231366 0.85
SCHEMBL2633929 0.85
SCHEMBL3306665 0.85
Carbamic Acid SCHEMBL18261668 0.79 TGFBR1 (0.39) CYP2D6CYP2C19CNR2KCNK3ALDH1A1
SCHEMBL6939465 0.77 LMNA (0.38) EPHX1ALDH1A1TDP1L3MBTL1CNR1
SCHEMBL28709191 0.73 CYP2D6 (0.42) CYP2D6CYP2C19ALDH1A1KMT2A
SCHEMBL21813551 0.71 CTSK (0.44) EPHX1CYP2D6CYP2C19L3MBTL1KMT2A
SCHEMBL21814100 0.71 CTSK (0.44) EPHX1CYP2D6CYP2C19L3MBTL1KMT2A
SCHEMBL21813554 0.71 CTSK (0.44) EPHX1CYP2D6CYP2C19L3MBTL1KMT2A
SCHEMBL30695447 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0900198-B1 NEW VITAMIN D DERIVATIVES WITH CARBO- OR HETEROCYCLIC SUBSTITUENTS AT C-25, A PROCESS FOR THEIR PRODUCTION, INTERMEDIATE PRODUCTS AND THEIR USE FOR PRODUCING MEDICAMENTS SCHERING AG (DE) 2003-03-12 EP disclosed
EP-0900198-A1 NEW VITAMIN D DERIVATIVES WITH CARBO- OR HETEROCYCLIC SUBSTITUENTS AT C-25, A PROCESS FOR THEIR PRODUCTION, INTERMEDIATE PRODUCTS AND THEIR USE FOR PRODUCING MEDICAMENTS Schering Aktiengesellschaft (DE) 1999-03-10 EP disclosed
WO-1997041096-A1 NEW VITAMIN D DERIVATIVES WITH CARBO- OR HETEROCYCLIC SUBSTITUENTS AT C-25, A PROCESS FOR THEIR PRODUCTION, INTERMEDIATE PRODUCTS AND THEIR USE FOR PRODUCING MEDICAMENTS SCHERING AKTIENGESELLSCHAFT (DE) 1997-11-06 WO disclosed