Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | KDM5C | P41229 | 1/20 | 0.39 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.39 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28219205 | 0.76 | ALDH1A1 (0.62) | CTSDALDH1A1GAAKDM4EKDM5C | |
| SCHEMBL49856 | 0.76 | ALDH1A1 (0.62) | CTSDALDH1A1GAAKDM4EKDM5C | |
| SCHEMBL6242259 | 0.75 | LMNA (0.50) | ALDH1A1MEN1KMT2A | |
| Acetone SCHEMBL22554792 | 0.74 | CTSD (0.59) | CTSDALDH1A1GAAKDM4EKDM5C | |
| Acetone SCHEMBL6392906 | 0.74 | CTSD (0.59) | CTSDALDH1A1GAAKDM4EKDM5C | |
| SCHEMBL8157871 | 0.74 | TSHR (0.52) | ALDH1A1MEN1KMT2A | |
| SCHEMBL7745348 | 0.74 | TSHR (0.52) | ALDH1A1MEN1KMT2A | |
| SCHEMBL8158107 | 0.74 | TSHR (0.52) | ALDH1A1MEN1KMT2A | |
| SCHEMBL7751275 | 0.74 | TSHR (0.52) | ALDH1A1MEN1KMT2A | |
| SCHEMBL406688 | 0.74 | CTSD (0.48) | CTSDALDH1A1GAAKDM4EKDM5C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1272456-A1 | HYDRAZIDE AND ALKOXYAMIDE ANGIOGENESIS INHIBITORS | Abbott Laboratories (US) | 2003-01-08 | — | — | EP | disclosed |
| WO-2001079157-A1 | HYDRAZIDE AND ALKOXYAMIDE ANGIOGENESIS INHIBITORS | ABBOTT LABORATORIES (US) | 2001-10-25 | — | — | WO | disclosed |