Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | BLM | P54132 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | GALR3 | O60755 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6760890 | 0.79 | TSHR (0.40) | TSHRALOX15CHRM2CHRM4CHRM1 | |
| SCHEMBL6376109 | 0.76 | L3MBTL1 (0.33) | — | |
| SCHEMBL14041835 | 0.76 | TSHR (0.37) | TSHRALOX15CHRM2CHRM4CHRM1 | |
| SCHEMBL1020469 | 0.76 | TDP1 (0.48) | TSHRALOX15CHRM2CHRM4CHRM1 | |
| SCHEMBL10771163 | 0.76 | — | — | |
| SCHEMBL8376143 | 0.75 | KDM4E (0.38) | ALOX15LMNABLMCYP1A2TDP1 | |
| Hydrochloric Acid SCHEMBL4305676 | 0.74 | TDP1 (0.47) | TSHRALOX15CHRM2CHRM4CHRM1 | |
| SCHEMBL9754046 | 0.72 | TSHR (0.35) | TSHRSMN1; SMN2 | |
| SCHEMBL25426024 | 0.71 | PGD (0.38) | — | |
| SCHEMBL28047126 | 0.71 | SMN1; SMN2 (0.40) | TSHRALOX15CHRM2CHRM4CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1311858-A2 | AFFINITY SELECTED SIGNATURE PEPTIDES FOR PROTEIN IDENTIFICATION AND QUANTIFICATION | PURDUE RESEARCH FOUNDATION (US) | 2003-05-21 | — | — | EP | disclosed |
| WO-2001086306-A2 | AFFINITY SELECTED SIGNATURE PEPTIDES FOR PROTEIN IDENTIFICATION AND QUANTIFICATION | PURDUE RESEARCH FOUNDATION (US) | 2001-11-15 | — | — | WO | disclosed |