Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6937354 | 0.88 | GAA (0.38) | LMNAMAPTHPGDSMN1; SMN2GAA | |
| SCHEMBL6939212 | 0.85 | BAZ2B (0.40) | LMNAMAPTHPGDSMN1; SMN2GAA | |
| SCHEMBL6937343 | 0.85 | POLB (0.32) | HPGDALDH1A1POLB | |
| SCHEMBL6938081 | 0.82 | ALDH1A1 (0.39) | HPGDGAAPDK2ALDH1A1POLB | |
| SCHEMBL38910 | 0.80 | ALDH1A1 (0.33) | LMNAMAPTHPGDSMN1; SMN2GAA | |
| SCHEMBL30750946 | 0.80 | ALDH1A1 (0.33) | LMNAMAPTHPGDSMN1; SMN2GAA | |
| SCHEMBL7561296 | 0.80 | ALDH1A1 (0.33) | LMNAMAPTHPGDSMN1; SMN2GAA | |
| SCHEMBL6939220 | 0.79 | HPGD (0.51) | LMNAMAPTHPGDSMN1; SMN2GAA | |
| SCHEMBL6935078 | 0.77 | HSD11B1 (0.31) | — | |
| SCHEMBL27320851 | 0.77 | MAPT (0.34) | LMNAMAPTHPGDSMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1061072-B1 | Pyrrolic compounds with a high herbicidal activity and their agronomic use | ISAGRO RICERCA SRL (IT) | 2003-05-14 | — | — | EP | disclosed |
| US-6391827-B1 | CONTROLLING WEEDS | ISAGRO RICERCA S.R.L. (IT) | 2002-05-21 | — | — | US | disclosed |
| EP-1061072-A1 | Pyrrolic compounds with a high herbicidal activity and their agronomic use | ISAGRO RICERCA S.r.l. (IT) | 2000-12-20 | — | — | EP | disclosed |