Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.31 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.31 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.31 |
| ▸ | PLAU | P00749 | 1/20 | 0.31 |
| ▸ | ELANE | P08246 | 1/20 | 0.31 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.31 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.31 |
| ▸ | ACLY | P53396 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6938081 | 0.87 | ALDH1A1 (0.39) | POLBAPEX1ALDH1A1HPGD | |
| SCHEMBL6937354 | 0.87 | GAA (0.38) | POLBAPEX1HPGDNOTUM | |
| SCHEMBL6940104 | 0.85 | LMNA (0.33) | POLBALDH1A1HPGD | |
| SCHEMBL6939220 | 0.85 | HPGD (0.51) | POLBALDH1A1HPGDTP53 | |
| SCHEMBL6939212 | 0.85 | BAZ2B (0.40) | POLBALDH1A1HPGD | |
| SCHEMBL6935078 | 0.83 | HSD11B1 (0.31) | — | |
| SCHEMBL6940513 | 0.80 | CYP2C19 (0.38) | ALDH1A1HPGDHSD17B10 | |
| SCHEMBL3689455 | 0.78 | RORC (0.36) | PLAUELANE | |
| SCHEMBL6939582 | 0.77 | PTGDR2 (0.35) | POLBAKR1C3AKR1C2 | |
| SCHEMBL6219513 | 0.77 | GRIK1 (0.33) | POLBAPEX1ALDH1A1TP53NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1061072-B1 | Pyrrolic compounds with a high herbicidal activity and their agronomic use | ISAGRO RICERCA SRL (IT) | 2003-05-14 | — | — | EP | disclosed |
| US-6391827-B1 | CONTROLLING WEEDS | ISAGRO RICERCA S.R.L. (IT) | 2002-05-21 | — | — | US | disclosed |
| EP-1061072-A1 | Pyrrolic compounds with a high herbicidal activity and their agronomic use | ISAGRO RICERCA S.r.l. (IT) | 2000-12-20 | — | — | EP | disclosed |