Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | ZDHHC7 | Q9NXF8 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4767066 | 0.81 | TSHR (0.37) | ALDH1A1ATMTSHR | |
| SCHEMBL7286728 | 0.81 | TSHR (0.37) | ALDH1A1ATMTSHR | |
| SCHEMBL7297178 | 0.79 | TSHR (0.35) | MAPTALDH1A1ATMTSHRRAB9A | |
| SCHEMBL7771226 | 0.76 | NAAA (0.41) | MAPTTSHRMAPK1L3MBTL1EPHX1 | |
| SCHEMBL14976393 | 0.74 | ALDH1A1 (0.35) | ALDH1A1ATMTSHRSMN1; SMN2HPGD | |
| SCHEMBL6139102 | 0.74 | CA14 (0.39) | TSHR | |
| SCHEMBL10526692 | 0.73 | ALDH1A1 (0.34) | ALDH1A1ATMTSHRSMN1; SMN2HPGD | |
| SCHEMBL8759979 | 0.73 | CTSL (0.37) | ALDH1A1ATMTSHRHPGD | |
| SCHEMBL10699431 | 0.73 | ALDH1A1 (0.45) | MAPTALDH1A1ATMTSHRSMN1; SMN2 | |
| SCHEMBL10699428 | 0.71 | ALDH1A1 (0.44) | ALDH1A1ATMTSHRSMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1330464-A2 | PHOSPHINO-AMINOPHOSPHINES, CATALYST COMPLEXES AND ENANTIOSELECTIVE HYDROGENATION | EASTMAN CHEMICAL COMPANY (US) | 2003-07-30 | — | — | EP | disclosed |
| WO-2002026750-A2 | PHOSPHINO-AMINOPHOSPHINES, CATALYST COMPLEXES AND ENANTIOSELECTIVE HYDROGENATION | EASTMAN CHEMICAL COMPANY (US) | 2002-04-04 | — | — | WO | disclosed |