Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 2/20 | 0.45 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.37 |
| ▸ | HEXA | P06865 | 1/20 | 0.37 |
| ▸ | HEXB | P07686 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 2/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | AHR | P35869 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18247480 | 0.69 | ALDH1A1 (0.42) | DAOMCL1TP53TSHRSMN1; SMN2 | |
| SCHEMBL7003290 | 0.66 | CNR2 (0.41) | DAOLMNATP53HPGDTSHR | |
| SCHEMBL24852495 | 0.66 | DAO (0.62) | DAODDB1CRBNMCL1HPGD | |
| SCHEMBL38660783 | 0.65 | DAO (0.47) | DAODDB1CRBNMCL1LMNA | |
| SCHEMBL5254835 | 0.64 | CCR2 (0.67) | DAOMCL1TSHRALDH1A1CNR2 | |
| SCHEMBL5786592 | 0.64 | TP53 (0.60) | TP53TSHRSMN1; SMN2HSD17B10ALDH1A1 | |
| SCHEMBL585623 | 0.64 | CA12 (0.53) | HEXAHEXBLMNAHPGDTSHR | |
| SCHEMBL25145160 | 0.64 | ALDH1A1 (0.41) | TP53HPGDTSHRALDH1A1CNR2 | |
| SCHEMBL15700116 | 0.63 | KDM4E (0.46) | TSHRALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL25145277 | 0.63 | CNR2 (0.48) | MCL1TP53TSHRALDH1A1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1333800-A2 | SKIN CONDITIONING COMPOSITIONS CONTAINING COMPOUNDS FOR MIMICKING THE EFFECT ON SKIN OF RETINOIC ACID | UNILEVER PLC (GB) | 2003-08-13 | — | — | EP | disclosed |
| WO-2002002074-A2 | SKIN CONDITIONING COMPOSITIONS CONTAINING COMPOUNDS FOR MIMICKING THE EFFECT ON SKIN OF RETINOIC ACID | UNILEVER PLC (GB) | 2002-01-10 | — | — | WO | disclosed |