Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 4/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CDK4 | P11802 | 3/20 | 0.39 |
| ▸ | CCND1 | P24385 | 3/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
| ▸ | PRKCB | P05771 | 1/20 | 0.36 |
| ▸ | PRKCA | P17252 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7002892 | 0.79 | HTR2C (0.54) | TSHRHPGDHSD17B10ALDH1A1MEN1 | |
| SCHEMBL7005488 | 0.77 | HPGD (0.47) | TSHRHPGDHSD17B10ALDH1A1LMNA | |
| SCHEMBL7004254 | 0.73 | DAO (0.46) | DAOTSHRHPGDHSD17B10ALDH1A1 | |
| SCHEMBL4992403 | 0.70 | CDK4 (0.78) | CDK4CCND1LMNAKMT2A | |
| SCHEMBL30701168 | 0.70 | CDK4 (0.78) | CDK4CCND1LMNAKMT2A | |
| Phosphoric Acid SCHEMBL6511008 | 0.67 | CDK4 (0.66) | CDK4CCND1LMNASMN1; SMN2MAPT | |
| SCHEMBL6940186 | 0.66 | DAO (0.45) | CNR2CNR1DAOTSHRHPGD | |
| SCHEMBL28236962 | 0.65 | CDK4 (0.81) | CDK4CCND1LMNAKMT2A | |
| SCHEMBL27356977 | 0.65 | PLG (0.49) | CDK4CCND1LMNA | |
| SCHEMBL6536824 | 0.64 | PSMB1 (0.47) | TSHRHPGDALDH1A1LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1200439-B1 | 1,2-DIHYDRO-1-OXO-PARAZINO(1,2-A) INDOLE DERIVATIVES | NOVUSPHARMA SPA (IT) | 2003-06-25 | — | — | EP | disclosed |