Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 14/20 | 0.52 |
| ▸ | METAP1 | P53582 | 11/20 | 0.52 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6491213 | 0.81 | METAP2 (0.59) | METAP2METAP1 | |
| SCHEMBL6562847 | 0.78 | METAP2 (0.48) | METAP2METAP1 | |
| SCHEMBL6563040 | 0.78 | METAP2 (0.47) | METAP2METAP1 | |
| SCHEMBL6486404 | 0.73 | METAP2 (0.56) | METAP2METAP1 | |
| SCHEMBL6941281 | 0.72 | METAP2 (0.48) | METAP2METAP1L3MBTL1 | |
| SCHEMBL6486546 | 0.72 | METAP2 (0.58) | METAP2METAP1 | |
| SCHEMBL6486992 | 0.71 | METAP2 (0.70) | METAP2METAP1 | |
| SCHEMBL6565042 | 0.70 | METAP2 (0.51) | METAP2METAP1 | |
| SCHEMBL6940131 | 0.70 | METAP2 (0.50) | METAP2METAP1 | |
| SCHEMBL6563403 | 0.69 | METAP2 (0.42) | METAP2METAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1272456-A1 | HYDRAZIDE AND ALKOXYAMIDE ANGIOGENESIS INHIBITORS | Abbott Laboratories (US) | 2003-01-08 | — | — | EP | claimed |
| WO-2001079157-A1 | HYDRAZIDE AND ALKOXYAMIDE ANGIOGENESIS INHIBITORS | ABBOTT LABORATORIES (US) | 2001-10-25 | — | — | WO | claimed |