Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TACR1 | P25103 | 2/20 | 0.40 |
| ▸ | CCR3 | P51677 | 5/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CCR5 | P51681 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6934444 | 0.85 | ALDH1A1 (0.44) | ALDH1A1TACR1CA1 | |
| SCHEMBL6942334 | 0.82 | MAPT (0.50) | ALDH1A1TACR1CA1 | |
| SCHEMBL6938929 | 0.82 | MAPT (0.50) | ALDH1A1CA1 | |
| SCHEMBL5375903 | 0.81 | CA1 (0.55) | ALDH1A1CA1 | |
| SCHEMBL11794387 | 0.80 | CA1 (0.54) | ALDH1A1CA1 | |
| SCHEMBL14292321 | 0.79 | MAPT (0.51) | ALDH1A1TACR1CA1 | |
| SCHEMBL18037841 | 0.79 | MAPT (0.51) | ALDH1A1TACR1CA1 | |
| SCHEMBL6939750 | 0.78 | TSHR (0.42) | ALDH1A1CA1CCR5 | |
| SCHEMBL6678153 | 0.76 | ALDH1A1 (0.40) | ALDH1A1CA1 | |
| SCHEMBL6940261 | 0.76 | SLC6A3 (0.44) | ALDH1A1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1043307-B1 | 3-amino-3-arylpropan-1-ol-derivates, their preparation and their use | GRUENENTHAL GMBH (DE) | 2003-06-04 | — | — | EP | disclosed |
| US-6410790-B1 | ANALGESICS | GRUENENTHAL GMBH (DE) | 2002-06-25 | — | — | US | disclosed |
| EP-1043307-A2 | 3-amino-3-arylpropan-1-ol-derivates, their preparation and their use | Grünenthal GmbH (DE) | 2000-10-11 | — | — | EP | disclosed |