Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 10/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6938981 | 0.99 | REN (0.53) | RENKMT2AHTTMEN1ALDH1A1 | |
| SCHEMBL6943202 | 0.89 | REN (0.55) | RENALDH1A1TSHRLMNAKDM4E | |
| Hydrochloric Acid SCHEMBL6947328 | 0.88 | REN (0.57) | RENALDH1A1TSHRLMNAKDM4E | |
| Hydrochloric Acid SCHEMBL6942968 | 0.88 | REN (0.56) | RENALDH1A1KDM4EGLAHPGD | |
| SCHEMBL6944430 | 0.85 | REN (0.51) | REN | |
| SCHEMBL6943818 | 0.85 | REN (0.43) | RENKMT2AHTTMEN1PDE4B | |
| Hydrochloric Acid SCHEMBL6947174 | 0.84 | REN (0.44) | RENKMT2AHTTMEN1PDE4B | |
| SCHEMBL6946620 | 0.84 | REN (0.51) | RENALDH1A1LMNA | |
| SCHEMBL6947152 | 0.84 | REN (0.51) | REN | |
| SCHEMBL6944413 | 0.83 | REN (0.48) | RENKMT2AALDH1A1TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003103653-A1 | METHODS OF TREATING ALZHEIMER'S DISEASE USING ARYL ALKANOIC ACID AMIDES | ELAN PHARMACEUTICALS, INC. (US) | 2003-12-18 | — | — | WO | claimed |
| WO-2003103653-A1 | METHODS OF TREATING ALZHEIMER'S DISEASE USING ARYL ALKANOIC ACID AMIDES | ELAN PHARMACEUTICALS, INC. (US) | 2003-12-18 | — | — | WO | disclosed |