Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 10/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6947174 | 0.99 | REN (0.44) | RENKMT2AMEN1HTTPDE4B | |
| SCHEMBL6943839 | 0.86 | REN (0.44) | RENKMT2AMEN1HTT | |
| SCHEMBL6943202 | 0.86 | REN (0.55) | REN | |
| Hydrochloric Acid SCHEMBL6940853 | 0.86 | REN (0.45) | RENKMT2AMEN1 | |
| Hydrochloric Acid SCHEMBL6942968 | 0.85 | REN (0.56) | REN | |
| Hydrochloric Acid SCHEMBL6947328 | 0.85 | REN (0.57) | RENTDP1 | |
| SCHEMBL6940726 | 0.85 | REN (0.52) | RENKMT2AMEN1HTTPDE4B | |
| Hydrochloric Acid SCHEMBL6938981 | 0.84 | REN (0.53) | RENKMT2AMEN1HTT | |
| SCHEMBL6943317 | 0.82 | REN (0.56) | RENKMT2AMEN1HTTTDP1 | |
| SCHEMBL6944413 | 0.80 | REN (0.48) | RENKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003103653-A1 | METHODS OF TREATING ALZHEIMER'S DISEASE USING ARYL ALKANOIC ACID AMIDES | ELAN PHARMACEUTICALS, INC. (US) | 2003-12-18 | — | — | WO | claimed |
| WO-2003103653-A1 | METHODS OF TREATING ALZHEIMER'S DISEASE USING ARYL ALKANOIC ACID AMIDES | ELAN PHARMACEUTICALS, INC. (US) | 2003-12-18 | — | — | WO | disclosed |