Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | DGAT1 | O75907 | 5/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 6/20 | 0.42 |
| ▸ | HTR3E | A5X5Y0 | 3/20 | 0.39 |
| ▸ | HTR3B | O95264 | 3/20 | 0.39 |
| ▸ | HTR3A | P46098 | 3/20 | 0.39 |
| ▸ | HTR3D | Q70Z44 | 3/20 | 0.39 |
| ▸ | HTR3C | Q8WXA8 | 3/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | NCF1 | P14598 | 1/20 | 0.39 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.39 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6940227 | 0.89 | MAPT (0.74) | MAPTKDM4EALDH1A1LMNAGAA | |
| Hydrochloric Acid SCHEMBL9120617 | 0.88 | MAPT (0.72) | MAPTKDM4EALDH1A1LMNAGAA | |
| SCHEMBL6941180 | 0.85 | ALDH1A1 (0.55) | MAPTKDM4EALDH1A1LMNAGAA | |
| SCHEMBL14765200 | 0.85 | MAPT (0.80) | MAPTKDM4EALDH1A1LMNAGAA | |
| SCHEMBL20639894 | 0.85 | MAPT (0.61) | MAPTKDM4EALDH1A1LMNAGAA | |
| SCHEMBL23354985 | 0.85 | MAPT (0.61) | MAPTKDM4EALDH1A1LMNAGAA | |
| SCHEMBL31618939 | 0.84 | ALDH1A1 (0.58) | MAPTKDM4EALDH1A1LMNAGAA | |
| SCHEMBL14764652 | 0.82 | MAPT (0.80) | MAPTKDM4EALDH1A1LMNAGAA | |
| SCHEMBL25160241 | 0.79 | SMN1; SMN2 (0.50) | MAPTKDM4EALDH1A1LMNAGAA | |
| SCHEMBL13114776 | 0.79 | ROCK2 (0.59) | MAPTKDM4EALDH1A1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0889881-B1 | NEW TRIAZOLES AS THERAPEUTIC AGENTS FOR FUNGAL INFECTIONS | NAEJA PHARMACEUTICAL INC (CA) | 2003-04-23 | — | — | EP | claimed |
| EP-0889881-A1 | NEW TRIAZOLES AS THERAPEUTIC AGENTS FOR FUNGAL INFECTIONS | SYNPHAR LABORATORIES INC. (CA) | 1999-01-13 | — | — | EP | claimed |
| WO-1998031675-A1 | NEW TRIAZOLES AS THERAPEUTIC AGENTS FOR FUNGAL INFECTIONS | SYNPHAR LABORATORIES, INC. (US) | 1998-07-23 | — | — | WO | claimed |