Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.30 |
| ▸ | CTSS | P25774 | 1/20 | 0.30 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27487429 | 1.00 | CTSL (0.30) | CTSLCTSSCTSKL3MBTL1PKM | |
| SCHEMBL6940914 | 0.77 | CYP1A2 (0.32) | CTSLCTSSCTSKL3MBTL1 | |
| SCHEMBL6940918 | 0.77 | CYP1A2 (0.32) | CTSLCTSSCTSKL3MBTL1 | |
| SCHEMBL6940923 | 0.76 | L3MBTL1 (0.34) | CTSKL3MBTL1PKM | |
| SCHEMBL27487428 | 0.76 | L3MBTL1 (0.34) | CTSKL3MBTL1PKM | |
| SCHEMBL6374179 | 0.66 | TDP1 (0.37) | — | |
| SCHEMBL6374183 | 0.66 | TDP1 (0.37) | — | |
| SCHEMBL14443175 | 0.65 | METAP1 (0.36) | PKM | |
| SCHEMBL13601089 | 0.65 | METAP1 (0.36) | PKM | |
| SCHEMBL9906042 | 0.64 | RIOK2 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0993442-B1 | HYDRAZINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2003-04-23 | — | — | EP | disclosed |
| US-6235787-B1 | ANTIINFLAMMATORY AGENTS; RHEUMATIC DISEASES; BONE DISORDERS; SKIN DISORDERS; MULTIPLE SCLEROSIS | HOFFMANN-LA ROCHE INC. | 2001-05-22 | — | — | US | disclosed |