Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 6/20 | 0.32 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.31 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27487428 | 1.00 | L3MBTL1 (0.34) | L3MBTL1PKMCTSKPLA2G4AHSPA5 | |
| SCHEMBL6940918 | 0.80 | CYP1A2 (0.32) | L3MBTL1CTSK | |
| SCHEMBL6940914 | 0.80 | CYP1A2 (0.32) | L3MBTL1CTSK | |
| SCHEMBL6945570 | 0.78 | LMNA (0.43) | CTSK | |
| SCHEMBL6943288 | 0.77 | TBXAS1 (0.42) | L3MBTL1 | |
| SCHEMBL27487429 | 0.76 | CTSL (0.30) | L3MBTL1PKMCTSK | |
| SCHEMBL6940925 | 0.76 | CTSL (0.30) | L3MBTL1PKMCTSK | |
| SCHEMBL15015925 | 0.73 | CA2 (0.46) | CTSK | |
| SCHEMBL28014684 | 0.70 | CA2 (0.47) | CTSK | |
| SCHEMBL6988869 | 0.65 | SMN1; SMN2 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0993442-B1 | HYDRAZINE DERIVATIVES | HOFFMANN LA ROCHE (CH) | 2003-04-23 | — | — | EP | disclosed |
| US-6235787-B1 | ANTIINFLAMMATORY AGENTS; RHEUMATIC DISEASES; BONE DISORDERS; SKIN DISORDERS; MULTIPLE SCLEROSIS | HOFFMANN-LA ROCHE INC. | 2001-05-22 | — | — | US | disclosed |