Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 3/20 | 0.34 |
| ▸ | PPARA | Q07869 | 2/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.34 |
| ▸ | RXRB | P28702 | 1/20 | 0.34 |
| ▸ | RXRG | P48443 | 1/20 | 0.34 |
| ▸ | REN | P00797 | 10/20 | 0.34 |
| ▸ | PTGES | O14684 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.33 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6940935 | 1.00 | MRGPRX4 (0.35) | MRGPRX4PPARGPPARARXRARXRB | |
| SCHEMBL6938930 | 0.84 | REN (0.45) | MRGPRX4PPARGPPARARXRARXRB | |
| SCHEMBL6947793 | 0.84 | REN (0.45) | MRGPRX4PPARGPPARARXRARXRB | |
| SCHEMBL6947788 | 0.84 | REN (0.45) | MRGPRX4PPARGPPARARXRARXRB | |
| SCHEMBL6938924 | 0.84 | REN (0.45) | MRGPRX4PPARGPPARARXRARXRB | |
| SCHEMBL6948152 | 0.83 | PPARA (0.43) | MRGPRX4PPARGPPARARENPTGES | |
| SCHEMBL6948146 | 0.83 | PPARA (0.43) | MRGPRX4PPARGPPARARENPTGES | |
| SCHEMBL6948398 | 0.82 | REN (0.36) | MRGPRX4PPARGPPARARXRARXRB | |
| SCHEMBL6948396 | 0.82 | REN (0.36) | MRGPRX4PPARGPPARARXRARXRB | |
| SCHEMBL6942881 | 0.80 | PPARA (0.42) | PPARARENTRPV1GRIN2DGRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003103653-A1 | METHODS OF TREATING ALZHEIMER'S DISEASE USING ARYL ALKANOIC ACID AMIDES | ELAN PHARMACEUTICALS, INC. (US) | 2003-12-18 | — | — | WO | disclosed |