Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 3/20 | 0.43 |
| ▸ | PPARG | P37231 | 3/20 | 0.43 |
| ▸ | REN | P00797 | 5/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.37 |
| ▸ | F9 | P00740 | 1/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | CASP9 | P55211 | 1/20 | 0.35 |
| ▸ | PTGES | O14684 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6948152 | 1.00 | PPARA (0.43) | PPARAPPARGRENABCB1ADRB3 | |
| SCHEMBL6948396 | 0.89 | REN (0.36) | PPARAPPARGRENMRGPRX4ACE2 | |
| SCHEMBL6948398 | 0.89 | REN (0.36) | PPARAPPARGRENMRGPRX4ACE2 | |
| SCHEMBL6940931 | 0.83 | MRGPRX4 (0.35) | PPARAPPARGRENMRGPRX4PTGES | |
| SCHEMBL6940935 | 0.83 | MRGPRX4 (0.35) | PPARAPPARGRENMRGPRX4PTGES | |
| SCHEMBL6947793 | 0.82 | REN (0.45) | PPARAPPARGRENMRGPRX4PTGES | |
| SCHEMBL6938930 | 0.82 | REN (0.45) | PPARAPPARGRENMRGPRX4PTGES | |
| SCHEMBL6947788 | 0.82 | REN (0.45) | PPARAPPARGRENMRGPRX4PTGES | |
| SCHEMBL6938924 | 0.82 | REN (0.45) | PPARAPPARGRENMRGPRX4PTGES | |
| SCHEMBL6942881 | 0.78 | PPARA (0.42) | PPARAREN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003103653-A1 | METHODS OF TREATING ALZHEIMER'S DISEASE USING ARYL ALKANOIC ACID AMIDES | ELAN PHARMACEUTICALS, INC. (US) | 2003-12-18 | — | — | WO | disclosed |