SCHEMBL6942881

SCHEMBL6942881

CC(C)C(CCCCCCc1ccc(C(C)(C)C)c(O)c1)C(=O)O

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 1/20 0.42
KAT8 Q9H7Z6 2/20 0.39
ACHE P22303 3/20 0.39
IGF1R P08069 3/20 0.38
ALOX15 P16050 3/20 0.38
GRIN2D O15399 1/20 0.38
GRIN2A Q12879 1/20 0.38
GRIN2B Q13224 1/20 0.38
GRIN2C Q14957 1/20 0.38
REN P00797 1/20 0.38
TRPV1 Q8NER1 1/20 0.36
SGMS1 Q86VZ5 1/20 0.35
SGMS2 Q8NHU3 1/20 0.35
CDK1 P06493 1/20 0.35
MEN1 O00255 1/20 0.34
POLB P06746 1/20 0.34
APEX1 P27695 1/20 0.34
KMT2A Q03164 1/20 0.34
CTDSP1 Q9GZU7 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6942877 1.00 PPARA (0.42) PPARAKAT8ACHEIGF1RALOX15
SCHEMBL21002247 0.81 ALOX15 (0.55) PPARAKAT8IGF1RALOX15CDK1
SCHEMBL6943972 0.80 KCNH2 (0.45)
SCHEMBL6943978 0.80 KCNH2 (0.45)
SCHEMBL6940648 0.80 TUBB4A (0.54) PPARAALOX15TRPV1MEN1APEX1
SCHEMBL6940652 0.80 TUBB4A (0.54) PPARAALOX15TRPV1MEN1APEX1
SCHEMBL6940935 0.80 MRGPRX4 (0.35) PPARAGRIN2DGRIN2AGRIN2BGRIN2C
SCHEMBL6940931 0.80 MRGPRX4 (0.35) PPARAGRIN2DGRIN2AGRIN2BGRIN2C
SCHEMBL21034788 0.79 ALOX15 (0.57) PPARAIGF1RALOX15CDK1
SCHEMBL6938930 0.79 REN (0.45) PPARARENTRPV1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2003103653-A1 METHODS OF TREATING ALZHEIMER'S DISEASE USING ARYL ALKANOIC ACID AMIDES ELAN PHARMACEUTICALS, INC. (US) 2003-12-18 WO disclosed