SCHEMBL6940971

SCHEMBL6940971

Cc1cc(N)ccc1-c1nn(C)c2c1CCC2

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.39
MEN1 O00255 2/20 0.39
MAPT P10636 2/20 0.39
THRB P10828 2/20 0.39
KMT2A Q03164 2/20 0.39
GAA P10253 1/20 0.39
NR4A1 P22736 1/20 0.39
PTK2B Q14289 1/20 0.39
CREBBP Q92793 3/20 0.38
STAT3 P40763 1/20 0.37
BRD4 O60885 2/20 0.35
RAD52 P43351 1/20 0.34
KDM4E B2RXH2 2/20 0.33
TGFBR1 P36897 1/20 0.33
C5AR1 P21730 1/20 0.33
GRM5 P41594 1/20 0.33
PTGS2 P35354 1/20 0.33
LMNA P02545 1/20 0.32
ALOX15 P16050 1/20 0.32
PDE10A Q9Y233 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7073628 0.70 DRD1 (0.48) ALDH1A1MEN1MAPTTHRBKMT2A
SCHEMBL19357254 0.68 CREBBP (0.33) CREBBPSTAT3KDM4EGRM5PTGS2
SCHEMBL6936302 0.67 AR (0.42) CREBBP
SCHEMBL20939482 0.67 POLB (0.34) ALDH1A1MEN1MAPTKMT2AGAA
SCHEMBL29777463 0.66 ALDH1A1 (0.65) ALDH1A1MEN1MAPTTHRBKMT2A
SCHEMBL30839745 0.66 ALDH1A1 (0.65) ALDH1A1MEN1MAPTTHRBKMT2A
SCHEMBL16280579 0.66 ALDH1A1 (0.65) ALDH1A1MEN1MAPTTHRBKMT2A
SCHEMBL63910 0.66 ALDH1A1 (0.65) ALDH1A1MEN1MAPTTHRBKMT2A
SCHEMBL13159948 0.65 KDM4E (0.46) ALDH1A1MAPTGAABRD4KDM4E
Hydrochloric Acid SCHEMBL4651933 0.64 ALDH1A1 (0.62) ALDH1A1MEN1MAPTTHRBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1370540-A1 ANTI-THROMBOTIC CARBOXYLIC ACID AMIDES, THE PRODUCTION THEREOF AND USE OF THE SAME AS MEDICAMENTS Boehringer Ingelheim Pharma GmbH & Co.KG (DE) 2003-12-17 EP disclosed
US-20020183519-A1 Antithrombotic carboxylic acid amides BOEHRINGER INGELHEIM PHARMA KG (DE) 2002-12-05 US disclosed
WO-2002072558-A1 ANTI-THROMBOTIC CARBOXYLIC ACID AMIDES, THE PRODUCTION THEREOF AND USE OF THE SAME AS MEDICAMENTS BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) 2002-09-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020183519-A1 Antithrombotic carboxylic acid amides SERPINC1, TFPI, F2 ALDH1A1 83/4885MEN1 2312/4885MAPT 4388/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.