Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 3/20 | 0.51 |
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.35 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28953820 | 0.88 | EPHX1 (0.54) | EPHX1TRPM8TRPA1ALDH1A1HPGD | |
| SCHEMBL18280698 | 0.86 | EPHX1 (0.45) | EPHX1TRPM8TRPA1ALDH1A1TRPV1 | |
| SCHEMBL30024164 | 0.84 | EPHX1 (0.54) | EPHX1TRPM8TRPA1ALDH1A1HPGD | |
| SCHEMBL21611750 | 0.83 | EPHX1 (0.53) | EPHX1TRPM8TRPA1ALDH1A1HPGD | |
| SCHEMBL8694409 | 0.77 | EPHX1 (0.61) | EPHX1TRPM8TRPA1ALDH1A1HPGD | |
| SCHEMBL19209892 | 0.76 | EPHX1 (0.47) | EPHX1TRPM8TRPA1ALDH1A1TRPV1 | |
| SCHEMBL31152467 | 0.76 | TRPM8 (0.48) | EPHX1TRPM8TRPA1ALDH1A1TRPV1 | |
| SCHEMBL584284 | 0.75 | EPHX1 (0.48) | EPHX1TRPM8TRPA1ALDH1A1HPGD | |
| SCHEMBL29029157 | 0.75 | EPHX1 (0.43) | EPHX1TRPM8TRPA1ALDH1A1HPGD | |
| SCHEMBL4312363 | 0.73 | EPHX1 (0.47) | EPHX1TRPM8TRPA1ALDH1A1TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2421820-A1 | COMPOUNDS HAVING A PHYSIOLOGICAL EFFECT | V. Mane Fils (FR) | 2012-02-29 | — | — | EP | disclosed |
| WO-2010122239-A1 | COMPOUNDS HAVING A PHYSIOLOGICAL EFFECT | V. MANE FILS (FR) | 2010-10-28 | — | — | WO | disclosed |