SCHEMBL584284

SCHEMBL584284

CC1CCC(C(C)C)C(C(CC(N)=O)C(=O)N(C)C)C1

nearest known ligand 0.48

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 3/20 0.48
TRPM8 Q7Z2W7 3/20 0.39
TRPA1 O75762 2/20 0.39
TRPV1 Q8NER1 6/20 0.33
ALDH1A1 P00352 3/20 0.33
HPGD P15428 1/20 0.33
CYP19A1 P11511 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29532276 0.91 EPHX1 (0.40) EPHX1TRPM8TRPA1
SCHEMBL21611750 0.85 EPHX1 (0.53) EPHX1TRPM8TRPA1TRPV1ALDH1A1
SCHEMBL1159626 0.76 EPHX1 (0.42) EPHX1TRPM8TRPA1TRPV1CYP19A1
SCHEMBL694115 0.75 EPHX1 (0.51) EPHX1TRPM8TRPA1TRPV1ALDH1A1
SCHEMBL30024164 0.75 EPHX1 (0.54) EPHX1TRPM8TRPA1TRPV1ALDH1A1
SCHEMBL28953820 0.75 EPHX1 (0.54) EPHX1TRPM8TRPA1TRPV1ALDH1A1
SCHEMBL1658606 0.72 EPHX1 (0.46) EPHX1TRPM8TRPA1TRPV1ALDH1A1
SCHEMBL584085 0.72 EPHX1 (0.46) EPHX1TRPM8TRPA1TRPV1ALDH1A1
SCHEMBL10593996 0.71 EPHX1 (0.51) EPHX1TRPM8TRPA1TRPV1ALDH1A1
SCHEMBL8694409 0.71 EPHX1 (0.61) EPHX1TRPM8TRPA1TRPV1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4103287-A1 COMPOSITIONS COMPRISING (BIO)-ALKANEDIOLS AND COOLING AGENTS Symrise AG (DE) 2022-12-21 EP claimed
WO-2022122134-A1 COMPOSITIONS WITH (BIO)-ALKANEDIOLS AND COOLING AGENTS SYMRISE AG (DE) 2022-06-16 WO claimed
WO-2022122903-A1 COMPOSITIONS COMPRISING (BIO)-ALKANEDIOLS AND COOLING AGENTS SYMRISE AG (DE) 2022-06-16 WO claimed
EP-3996505-A1 SYNERGISTIC FORMULATIONS FOR CONTROL AND REPELLENCY OF BITING ARTHROPODS Bedoukian Research, Inc. (US) 2022-05-18 EP claimed
EP-3996506-A1 FORMULATIONS FOR CONTROL AND REPELLENCY OF BITING ARTHROPODS Bedoukian Research, Inc. (US) 2022-05-18 EP claimed
EP-2785309-B1 COSMETIC AEROSOL SPRAY WITH LASTING FRESHNESS EFFECT HENKEL AG & CO KGAA (DE) 2017-07-12 EP claimed
EP-1924148-B1 CONFECTIONERY COMPOSITION INCLUDING AN ELASTOMERIC COMPONENT, A COOKED SACCHARIDE COMPONENT, AND A SENSATE INTERCONTINENTAL GREAT BRANDS LLC (US) 2016-07-20 EP claimed
WO-2014198366-A1 GLOVE WITH A COOLING EFFECT CARL FREUDENBERG KG (DE) 2014-12-18 WO claimed
EP-2785309-A1 COSMETIC AEROSOL SPRAY WITH LASTING FRESHNESS EFFECT Henkel AG & Co. KGaA (DE) 2014-10-08 EP claimed
US-20140271518-A1 COSMETIC AEROSOL SPRAY WITH LASTING FRESHNESS EFFECT HENKEL AG & CO. KGAA (DE) 2014-09-18 US claimed
EP-2758029-A1 WATER-FREE FORMULATIONS HAVING A COOLING EFFECT Henkel AG&Co. KGAA (DE) 2014-07-30 EP claimed
WO-2013079349-A1 COSMETIC AEROSOL SPRAY WITH LASTING FRESHNESS EFFECT HENKEL AG & CO. KGAA (DE) 2013-06-06 WO claimed
WO-2013041611-A1 WATER-FREE FORMULATIONS HAVING A COOLING EFFECT HENKEL AG & CO. KGAA (DE) 2013-03-28 WO claimed
EP-2168957-B1 Alkyl-substituted tetrahydropyranes as aromatic materials SYMRISE AG (DE) 2012-02-15 EP claimed
CN-122028893-A Composition and method for producing the same 奇华顿股份有限公司 2026-05-12 CN disclosed
US-20240277012-A1 DUPLICATE BEVERAGE WANG JIE (US) 2024-08-22 US disclosed
US-20240108040-A1 HIGH INTENSITY SWEETENERS FIRMENICH INCORPORATED (US) 2024-04-04 US disclosed
WO-2014026842-A2 COSMETIC COMPOUNDS HAVING TIME-DELAYED ACTIVE INGREDIENT RELEASE HENKEL AG & CO. KGAA (DE) 2014-02-20 WO disclosed
WO-2013079349-A1 COSMETIC AEROSOL SPRAY WITH LASTING FRESHNESS EFFECT HENKEL AG & CO. KGAA (DE) 2013-06-06 WO disclosed
WO-2013041611-A1 WATER-FREE FORMULATIONS HAVING A COOLING EFFECT HENKEL AG & CO. KGAA (DE) 2013-03-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240108040-A1 HIGH INTENSITY SWEETENERS TAS2R40, TAS2R60, TAS1R1 EPHX1 3026/4885TRPM8 180/4885TRPA1 179/4885
US-20140271518-A1 COSMETIC AEROSOL SPRAY WITH LASTING FRESHNESS EFFECT ALOX5, CUTA, OR51E2 EPHX1 963/4885TRPM8 308/4885TRPA1 241/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.