Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC10A2 | Q12908 | 2/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | EDNRB | P24530 | 1/20 | 0.31 |
| ▸ | EDNRA | P25101 | 1/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.30 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.30 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.30 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6935693 | 0.90 | — | — | |
| SCHEMBL7819319 | 0.88 | ESR1 (0.33) | NR1I2 | |
| SCHEMBL7813213 | 0.88 | ESR1 (0.33) | NR1I2 | |
| SCHEMBL6937839 | 0.87 | ESR1 (0.34) | NR1I2 | |
| SCHEMBL7812177 | 0.86 | ESR1 (0.31) | NR1I2 | |
| SCHEMBL5854319 | 0.80 | MTNR1A (0.31) | MTNR1BMTNR1AKDM1A | |
| SCHEMBL7813218 | 0.79 | SIGMAR1 (0.32) | — | |
| SCHEMBL7128086 | 0.76 | MTNR1A (0.32) | MTNR1BMTNR1A | |
| SCHEMBL5854887 | 0.76 | MTNR1A (0.32) | MTNR1BMTNR1A | |
| SCHEMBL5856061 | 0.76 | ESR1 (0.40) | MTNR1BMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1240156-A4 | 3-METHYL-CHROMANE OR THIOCHROMANE DERIVATIVES | CHUGAI PHARMACEUTICAL CO LTD (JP) | 2003-04-16 | — | — | EP | disclosed |
| EP-1240156-A1 | 3-METHYL-CHROMANE OR THIOCHROMANE DERIVATIVES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001042237-A1 | 3-METHYL-CHROMANE OR THIOCHROMANE DERIVATIVES | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2001-06-14 | — | — | WO | disclosed |