Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 10/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.35 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | STS | P08842 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6940299 | 0.90 | SLC6A2 (0.44) | SLC6A2SLC6A4OPRL1OPRM1NISCH | |
| SCHEMBL6937455 | 0.85 | PSEN1 (0.37) | — | |
| SCHEMBL6939734 | 0.83 | SLC6A3 (0.35) | SLC6A2SLC6A4STS | |
| SCHEMBL6940264 | 0.83 | SLC6A2 (0.44) | SLC6A2SLC6A4OPRL1OPRM1NISCH | |
| SCHEMBL6939083 | 0.82 | SLC6A2 (0.41) | SLC6A2SLC6A4OPRM1STS | |
| SCHEMBL6936266 | 0.80 | MEN1 (0.32) | RAB9A | |
| SCHEMBL6680122 | 0.79 | SLC6A2 (0.42) | SLC6A2SLC6A4OPRL1OPRM1NISCH | |
| SCHEMBL6677450 | 0.78 | TMEM97 (0.40) | SLC6A2SLC6A4OPRL1OPRM1 | |
| SCHEMBL6936116 | 0.78 | SLC6A9 (0.39) | SLC6A2SLC6A4OPRL1OPRM1 | |
| SCHEMBL6676290 | 0.78 | SLC6A2 (0.41) | SLC6A2SLC6A4OPRL1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1043307-B1 | 3-amino-3-arylpropan-1-ol-derivates, their preparation and their use | GRUENENTHAL GMBH (DE) | 2003-06-04 | — | — | EP | disclosed |
| EP-1043307-A2 | 3-amino-3-arylpropan-1-ol-derivates, their preparation and their use | Grünenthal GmbH (DE) | 2000-10-11 | — | — | EP | disclosed |