Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 12/20 | 0.52 |
| ▸ | MAOA | P21397 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | MIF | P14174 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 3-Coumaranone SCHEMBL29420742 | 1.00 | PKM (0.56) | PKMTSHRMAOBMAOAMAPT | |
| SCHEMBL2929432 | 0.91 | PKM (0.52) | PKMTSHRMAOBMAOAMAPT | |
| SCHEMBL28709151 | 0.86 | PKM (0.63) | PKMTSHRMAOBMAOAMAPT | |
| SCHEMBL10460744 | 0.83 | PKM (0.48) | PKMTSHRMAOBMAOAMAPT | |
| 3-Coumaranone SCHEMBL31042958 | 0.83 | MAOB (0.41) | PKMTSHRMAOBMAOAMAPT | |
| 3-Coumaranone SCHEMBL29031733 | 0.82 | PKM (0.44) | PKMTSHRMAOBMAOAMAPT | |
| 3-Coumaranone SCHEMBL9571710 | 0.82 | MAOB (0.51) | PKMTSHRMAOBMAOAMAPT | |
| Acetic Acid SCHEMBL8221392 | 0.81 | HSD17B10 (0.44) | PKMTSHRMAOBMAOAMAPT | |
| SCHEMBL8647765 | 0.78 | MAOB (0.45) | PKMTSHRMAOBMAOAMAPT | |
| SCHEMBL7380169 | 0.78 | MAOA (0.60) | PKMTSHRMAOBMAOAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1502 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119909056-A | Application of 3-oxo-benzofuran compounds in preparation of SNX3 inhibitor and lung fibrosis treatment drug | 中山大学 | 2025-05-02 | — | — | CN | claimed |
| CN-119822527-A | Trace type compound scale inhibitor based on benzofuran fluorescent agent, and preparation method and application thereof | 华北电力科学研究院有限责任公司 | 2025-04-15 | — | — | CN | claimed |
| WO-2025070233-A1 | PHOTOSENSITIVE COMPOSITION, CURED PRODUCT, ELECTRONIC COMPONENT, AND METHOD FOR PRODUCING CURED PRODUCT | 東レ株式会社 | 2025-04-03 | — | — | WO | claimed |
| WO-2025033225-A1 | CURABLE COMPOSITION, FILM, OPTICAL FILTER, SOLID-STATE IMAGING ELEMENT, AND IMAGE DISPLAY DEVICE | 富士フイルム株式会社 | 2025-02-13 | — | — | WO | claimed |
| CN-116239562-B | Method for synthesizing doxepin hydrochloride by taking benzofuranone as raw material | 江苏师范大学 | 2024-12-31 | — | — | CN | claimed |
| CN-114948927-B | Application of 3-benzofuranone derivative containing benzylidene in preparation of antitumor drugs | 无锡九基生物科技有限公司 | 2024-10-15 | — | — | CN | claimed |
| CN-118772165-A | Diphenyl pyridine benzene topoisomerase inhibitor based on benzofuran and N-heterocyclic compound structure, and preparation method and application thereof | 平原实验室 | 2024-10-15 | — | — | CN | claimed |
| CN-118063419-A | Orange ketoxime ester photoinitiator, preparation method and application thereof | 大连理工大学 | 2024-05-24 | — | — | CN | claimed |
| CN-115557855-B | Polysubstituted 2-hydroxy diphenyl ketone compound and preparation method and application thereof | 郑州铁路职业技术学院 | 2024-05-07 | — | — | CN | claimed |
| CN-117919222-A | Application of 3-oxo-benzofuran compounds in preparation of medicines for treating heart failure related diseases | 中山大学 | 2024-04-26 | — | — | CN | claimed |
| EP-0399748-B1 | Process for making 2-oxindole-1-carboxamides | PFIZER (US) | 1996-01-24 | — | — | EP | claimed |
| EP-0483772-B1 | Aminocoumaran derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1995-09-13 | — | — | EP | claimed |
| EP-0199543-B1 | HETEROCYCLIC AMIDE DERIVATIVES | ICI AMERICAS INC. (US) | 1991-12-04 | — | — | EP | claimed |
| EP-0156603-B1 | 3-SUBSTITUTED 2-OXINDOLE-1-CARBOXAMIDES AS ANALGESIC AND ANTI-INFLAMMATORY AGENTS | PFIZER INC. (US) | 1989-08-23 | — | — | EP | claimed |
| EP-0164860-B1 | N,3-DISUBSTITUTED 2-OXINDOLE-1-CARBOXAMIDES AS ANALGESIC AND ANTIINFLAMMATORY AGENTS | PFIZER INC. (US) | 1989-07-05 | — | — | EP | claimed |
| EP-0056157-B1 | USE OF 7-HYDROXY-COUMARIN COMPOUNDS FOR IMPREGNATING PAPER | BAYER AG (DE) | 1985-05-29 | — | — | EP | claimed |
| EP-0065393-B1 | PYRROLE DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-12-27 | — | — | EP | claimed |
| EP-0034521-B1 | ANALGESIC DRUG CONTAINING 1-(3'-BENZOFURYL)-4-BENZYLPIPERAZINE AND PROCESS FOR ITS PREPARATION | Buzas, André (FR) | 1983-03-23 | — | — | EP | claimed |
| EP-0010360-B1 | PROSTANE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND THEIR PHARMACEUTICAL COMPOSITIONS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-06-02 | — | — | EP | claimed |
| EP-0034521-A1 | Analgesic drug containing 1-(3'-benzofuryl)-4-benzylpiperazine and process for its preparation | Buzas, André (FR) | 1981-08-26 | — | — | EP | claimed |