Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 3/20 | 0.46 |
| ▸ | PPARG | P37231 | 2/20 | 0.44 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.43 |
| ▸ | BID | P55957 | 3/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.43 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.43 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.43 |
| ▸ | EP300 | Q09472 | 1/20 | 0.43 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.43 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.43 |
| ▸ | KAT5 | Q92993 | 1/20 | 0.43 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | DRD5 | P21918 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8099840 | 0.99 | THRA (0.49) | THRATHRBPPARAPPARGMGLL | |
| SCHEMBL10180973 | 0.97 | THRA (0.47) | THRATHRBPPARAPPARGMGLL | |
| Iodide SCHEMBL9652564 | 0.94 | DRD2 (0.44) | THRATHRBPPARAMGLLDRD2 | |
| SCHEMBL2829914 | 0.93 | DRD2 (0.44) | THRATHRBPPARAMGLLDRD2 | |
| Iodide SCHEMBL8734866 | 0.90 | PPARA (0.42) | THRATHRBPPARAPPARGKCNH2 | |
| Iodide SCHEMBL8737228 | 0.90 | PPARA (0.42) | THRATHRBPPARAPPARGKCNH2 | |
| Iodide SCHEMBL8386680 | 0.88 | PPARA (0.46) | THRATHRBPPARAPPARGKCNH2 | |
| SCHEMBL4376769 | 0.87 | DRD2 (0.46) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL14157502 | 0.86 | PPARA (0.47) | THRATHRBPPARAPPARGKCNH2 | |
| SCHEMBL10180862 | 0.86 | THRA (0.45) | THRATHRBPPARAPPARGMGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019162035-A1 | COMPOSITION FOR GENERATING AN ADHESIVE COMPOUND, IN PARTICULAR FOR ENCAPSULATION OF AN ELECTRONIC ASSEMBLY | TESA SE (DE) | 2019-08-29 | — | — | WO | disclosed |
| EP-1004605-B1 | Radiation curable compositions containing alkenyl ether functional polyisobutylenes | DOW CORNING (US) | 2003-12-03 | — | — | EP | disclosed |
| EP-1004613-A2 | Vinyl ether functional organopolysiloxanes and their use in radiation curable silicone compositions | DOW CORNING CORPORATION (US) | 2000-05-31 | — | — | EP | disclosed |
| EP-1004612-A1 | Vinyl ether-functional organopolysiloxanes and their use in radiation-curable silicone compositions | DOW CORNING CORPORATION (US) | 2000-05-31 | — | — | EP | disclosed |
| EP-1004647-A1 | Radiation curable silicone compositions | DOW CORNING CORPORATION (US) | 2000-05-31 | — | — | EP | disclosed |
| EP-1004605-A1 | Radiation curable compositions containing alkenyl ether functional polyisobutylenes | DOW CORNING CORPORATION (US) | 2000-05-31 | — | — | EP | disclosed |
| EP-1004637-A1 | Radiation curable compositions | DOW CORNING CORPORATION (US) | 2000-05-31 | — | — | EP | disclosed |
| US-6069185-A | LOW CURE ENERGY, HAVE A HIGH MOISTURE VAPOR BARRIER, HIGH DAMPING CHARACTERISTICS, AND A HIGH REFRACTIVE INDEX, AND PROVIDE A BARRIER TO CORROSIVE VAPORS AND HAVE MAINTAINED OR ENHANCED MODULUS, TENSILE STRENGTH, AND TOUGHNESS | DOW CORNING ASIA, LTD. (JP) | 2000-05-30 | — | — | US | disclosed |
| US-6028124-A | Radiation curable compositions | DOW CORNING CORPORATION (US) | 2000-02-22 | — | — | US | disclosed |