SCHEMBL6941489

SCHEMBL6941489

CCOCCS(=O)(=O)c1ccccc1N

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.46
CA9 Q16790 3/20 0.44
CA2 P00918 3/20 0.44
CYP2C9 P11712 2/20 0.44
CA12 O43570 2/20 0.44
CA1 P00915 2/20 0.44
CA4 P22748 2/20 0.44
CA6 P23280 1/20 0.44
CA5A P35218 1/20 0.44
CA7 P43166 1/20 0.44
CA14 Q9ULX7 1/20 0.44
CA5B Q9Y2D0 1/20 0.44
KYNU Q16719 2/20 0.43
LOX P28300 1/20 0.41
HTR6 P50406 1/20 0.41
PIK3C3 Q8NEB9 1/20 0.40
ALDH1A1 P00352 4/20 0.38
HSD17B10 Q99714 3/20 0.38
KDM4E B2RXH2 2/20 0.38
MAPT P10636 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL375690 0.80 GAA (0.54) GAACA9CA2CYP2C9CA12
SCHEMBL1170678 0.78 KYNU (0.47) GAACA9CA2CYP2C9CA12
SCHEMBL1972988 0.78 GAA (0.60) GAACA9CA2CYP2C9CA12
SCHEMBL6936905 0.78 CA2 (0.51) GAACA9CA2CYP2C9CA12
SCHEMBL27552427 0.76 GAA (0.48) GAACA9CA2CYP2C9CA12
SCHEMBL8356104 0.75 GAA (0.44) GAACA9CA2CYP2C9CA12
SCHEMBL9453064 0.75 GAA (0.47) GAACA9CA2CYP2C9CA12
SCHEMBL10826348 0.74 GAA (0.56) GAACA9CA2CYP2C9CA12
SCHEMBL9809463 0.74 KYNU (0.44) GAACA9CA2CYP2C9CA12
SCHEMBL11059561 0.73 GAA (0.46) GAACA9CA2CYP2C9CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1066349-B1 REACTIVE BLACK DYES CONTAINING ACETOXYETHYLSULFONE MOIETIES KOREA RES INST CHEM TECH (KR) 2003-06-11 EP disclosed
US-6326474-B1 DIAZOTIZING AN AMINOPHENYL-B-ACETOXYETHYL SULFONE; NEUTRALIZATION KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2001-12-04 US disclosed