Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 3/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 7/20 | 0.38 |
| ▸ | QDPR | P09417 | 3/20 | 0.37 |
| ▸ | SNCA | P37840 | 3/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | IP6K2 | Q9UHH9 | 2/20 | 0.36 |
| ▸ | POLH | Q9Y253 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ST6GAL1 | P15907 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9764763 | 0.80 | ESR1 (0.37) | — | |
| SCHEMBL13519167 | 0.74 | CA1 (0.45) | KDM4ECYP3A4MAPTMEN1CYP2C9 | |
| SCHEMBL6272816 | 0.73 | HSD17B3 (0.40) | APPPTGS2KDM4EMAPTMAPK1 | |
| SCHEMBL5848037 | 0.72 | — | — | |
| SCHEMBL668518 | 0.72 | BACE1 (0.39) | MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL10589880 | 0.69 | KIF11 (0.38) | PTGS2HSD17B10TNKSALDH1A1 | |
| SCHEMBL338028 | 0.65 | APP (1.00) | APPALOX5QDPRSNCACYP3A4 | |
| SCHEMBL345406 | 0.64 | — | — | |
| SCHEMBL6643593 | 0.63 | — | — | |
| SCHEMBL4750813 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6759367-B2 | COMPRISING THERMOSENSITIVE ELEMENT AND SUPPORT, THE THERMOSENSITIVE ELEMENT CONTAINING A SUBSTANTIALLY LIGHT-INSENSITIVE ORGANIC SILVER SALT, A 3,4-DIHYDROXYBENZENE COMPOUND, A BINDER | AGFA-GEVAERT (BE) | 2004-07-06 | — | — | US | disclosed |
| US-20030054958-A1 | Thermographic recording material with improved print archivability without loss in printability | AGFA-GEVAERT (BE) | 2003-03-20 | — | — | US | disclosed |
| EP-1245404-A1 | Thermographic recording material providing prints with good image density and tone having improved archivability | Agfa-Gevaert (BE) | 2002-10-02 | — | — | EP | disclosed |