SCHEMBL338028

SCHEMBL338028

Oc1ccc(-c2ccc(O)c(O)c2)cc1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
APP P05067 3/20 1.00
ALOX5 P09917 6/20 0.78
QDPR P09417 3/20 0.67
SNCA P37840 5/20 0.62
CYP3A4 P08684 2/20 0.55
ALOX15 P16050 1/20 0.55
HSD17B10 Q99714 1/20 0.55
MAPT P10636 1/20 0.52
CYP17A1 P05093 1/20 0.52
CYP19A1 P11511 1/20 0.52
CYP11B1 P15538 1/20 0.52
CYP11B2 P19099 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12084357 0.94 APP (0.88) APPALOX5QDPRSNCACYP3A4
SCHEMBL3814886 0.88 ALOX5 (1.00) APPALOX5QDPRSNCA
SCHEMBL30016853 0.88 APP (0.90) APPALOX5QDPRCYP3A4ALOX15
SCHEMBL13389037 0.88 APP (1.00) APPALOX5QDPRSNCACYP3A4
SCHEMBL1235644 0.88 ALOX5 (1.00) APPALOX5QDPRSNCA
SCHEMBL25420702 0.86 APP (0.74) APPALOX5QDPRSNCACYP3A4
SCHEMBL928289 0.86 ALOX5 (1.00) APPALOX5QDPRALOX15HSD17B10
SCHEMBL29848221 0.86 ALOX5 (1.00) APPALOX5QDPRALOX15HSD17B10
SCHEMBL16641092 0.84 ALOX5 (0.75) APPALOX5QDPRSNCA
SCHEMBL13016698 0.84 APP (0.70) APPALOX5QDPR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 351 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230149323-A1 INHIBITORS OF THE INTERACTION OF THE UPAR/FPRS RECEPTORS ORPHA BIOTECH S.R.L. (IT) 2023-05-18 US claimed
EP-4125833-A1 INHIBITORS OF THE INTERACTION OF THE UPAR/FPRS RECEPTORS Orpha Biotech S.r.l. (IT) 2023-02-08 EP claimed
CN-107496433-A A kind of biphenyl compound is in the application for preparing oxidative stress and inducing an illness in medicine 山东大学 2017-12-22 CN claimed
US-20250321481-A1 PHOTOSENSITIVE RESIN COMPOSITION TOKYO OHKA KOGYO CO LTD (JP) 2025-10-16 US disclosed
CN-119875305-B Halogen-free flame-retardant temperature-resistant epoxy resin and preparation method thereof 湖北珍正峰新材料有限公司 2025-06-13 CN disclosed
US-12312489-B2 Curable composition, cured product and method for forming insulating film TOKYO OHKA KOGYO CO., LTD. (JP) 2025-05-27 US disclosed
CN-119875305-A Halogen-free flame-retardant temperature-resistant epoxy resin and preparation method thereof 湖北珍正峰新材料有限公司 2025-04-25 CN disclosed
EP-3935124-B1 HEAT TRANSFER COMPOSITIONS COMPRISING R-1225YE(E), HFO-1234YF, R-32 AND CO2 CHEMOURS CO FC LLC (US) 2024-06-26 EP disclosed
EP-3935123-B1 HEAT TRANSFER COMPOSITIONS COMPRISING R-1225YE(E), HFO-1234YF, R-32 AND R-125 CHEMOURS CO FC LLC (US) 2024-06-19 EP disclosed
EP-3935122-B1 HEAT TRANSFER COMPOSITIONS COMPRISING R-1225YE(E) CHEMOURS CO FC LLC (US) 2024-05-08 EP disclosed
EP-4361236-A2 REFRIGERANT COMPOSITION The Chemours Company FC, LLC (US) 2024-05-01 EP disclosed
EP-0760378-A1 Polymer scale deposition preventive agent SHIN-ETSU CHEMICAL CO., LTD. (JP) 1997-03-05 EP disclosed
EP-0370355-B1 RADIATION-POLYMERISABLE MIXTURE, AND REGISTRATION MATERIAL PREPARED THEREOF HOECHST AKTIENGESELLSCHAFT (DE) 1993-09-29 EP disclosed
US-5241003-A Post-treated polyisobutenyl succinimide; crankcase, transmission oils ETHYL PETROLEUM ADDITIVES, INC. (US) 1993-08-31 US disclosed
US-5137980-A Reacting polyisobutene with aacidic reactant; super atmospheric pressure; low tar rating ETHYL PETROLEUM ADDITIVES, INC. (US) 1992-08-11 US disclosed
US-5035970-A Encapsulated toner compositions and processes thereof XEROX CORPORATION (US) 1991-07-30 US disclosed
EP-0370355-A1 Radiation-polymerisable mixture, and registration material prepared thereof HOECHST AKTIENGESELLSCHAFT (DE) 1990-05-30 EP disclosed
EP-0212439-B1 POLYMERS AND RADIOSENSITIVE COMPOSITIONS CONTAINING THEM HOECHST AKTIENGESELLSCHAFT (DE) 1990-05-16 EP disclosed
US-4910119-A Blend of acrylated ester, unsaturated compound and photoinitiator HOECHST AKTIENGESELLSCHAFT (DE) 1990-03-20 US disclosed
EP-0212439-A2 Polymers and radiosensitive compositions containing them HOECHST AKTIENGESELLSCHAFT (DE) 1987-03-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230149323-A1 INHIBITORS OF THE INTERACTION OF THE UPAR/FPRS RECEPTORS FPR3, FPR1, PLAUR APP 1459/4885ALOX5 221/4885QDPR 1593/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.