Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.70 |
| ▸ | LMNA | P02545 | 2/20 | 0.70 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | CFTR | P13569 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MYC | P01106 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10360804 | 0.90 | ALDH1A1 (0.77) | ALDH1A1LMNATSHRHSD17B10CFTR | |
| SCHEMBL5253873 | 0.86 | ALDH1A1 (0.62) | ALDH1A1LMNATSHRHSD17B10CFTR | |
| SCHEMBL1629682 | 0.85 | ALDH1A1 (0.70) | ALDH1A1LMNATSHRHSD17B10CFTR | |
| SCHEMBL2655484 | 0.85 | ALDH1A1 (0.70) | ALDH1A1LMNATSHRHSD17B10CFTR | |
| SCHEMBL29875722 | 0.85 | ALDH1A1 (0.70) | ALDH1A1LMNATSHRHSD17B10CFTR | |
| SCHEMBL2093831 | 0.85 | ALDH1A1 (0.64) | ALDH1A1LMNATSHRHSD17B10CFTR | |
| SCHEMBL7520106 | 0.84 | ALDH1A1 (0.64) | ALDH1A1LMNATSHRHSD17B10CFTR | |
| SCHEMBL8412585 | 0.84 | ALDH1A1 (0.78) | ALDH1A1LMNATSHRHSD17B10CFTR | |
| SCHEMBL1920110 | 0.84 | ALDH1A1 (0.68) | ALDH1A1LMNATSHRHSD17B10CFTR | |
| SCHEMBL4739142 | 0.84 | ALDH1A1 (0.68) | ALDH1A1LMNATSHRHSD17B10CFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1284260-A1 | TYROSINE PHOSPHATASE INHIBITORS | Takeda Chemical Industries, Ltd. (JP) | 2003-02-19 | — | — | EP | disclosed |