SCHEMBL1920110

SCHEMBL1920110

COC(=O)c1ccccc1CCCl

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.68
LMNA P02545 2/20 0.68
TSHR P16473 2/20 0.52
HSD17B10 Q99714 2/20 0.50
CFTR P13569 1/20 0.50
HIF1A Q16665 1/20 0.49
KDM4E B2RXH2 3/20 0.49
POLB P06746 2/20 0.49
KMT2A Q03164 2/20 0.49
ATM Q13315 1/20 0.49
GLA P06280 1/20 0.46
SLC6A4 P31645 1/20 0.46
SLC6A3 Q01959 1/20 0.46
HTT P42858 2/20 0.46
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
CA5A P35218 1/20 0.45
CA9 Q16790 1/20 0.45
MAPT P10636 1/20 0.45
ALOX15 P16050 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10360804 0.89 ALDH1A1 (0.77) ALDH1A1LMNATSHRHSD17B10CFTR
SCHEMBL2802347 0.85 ALDH1A1 (0.62) ALDH1A1LMNATSHRHSD17B10CFTR
SCHEMBL29875722 0.84 ALDH1A1 (0.70) ALDH1A1LMNATSHRHSD17B10CFTR
SCHEMBL6941818 0.84 ALDH1A1 (0.70) ALDH1A1LMNATSHRHSD17B10CFTR
SCHEMBL2655484 0.84 ALDH1A1 (0.70) ALDH1A1LMNATSHRHSD17B10CFTR
SCHEMBL1629682 0.84 ALDH1A1 (0.70) ALDH1A1LMNATSHRHSD17B10CFTR
SCHEMBL1151042 0.83 ALDH1A1 (0.64) ALDH1A1LMNATSHRHSD17B10CFTR
SCHEMBL31567935 0.82 ALDH1A1 (0.68) ALDH1A1LMNATSHRHSD17B10CFTR
SCHEMBL4739142 0.82 ALDH1A1 (0.68) ALDH1A1LMNATSHRHSD17B10CFTR
SCHEMBL1918904 0.82 ALDH1A1 (0.68) ALDH1A1LMNATSHRHSD17B10CFTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230371508-A1 COMPOSITIONS AND METHODS FOR KILLING INSECT AND NON-INSECT PESTS THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE 2023-11-23 US disclosed
US-11805776-B2 Compositions and methods for killing insect and non-insect pests THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 2023-11-07 US disclosed
US-20220183287-A1 METHODS FOR KILLING PESTS THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE 2022-06-16 US disclosed
WO-2022125885-A1 METHODS FOR KILLING PESTS THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 2022-06-16 WO disclosed
WO-2019143506-A1 COMPOSITIONS AND METHODS FOR KILLING INSECT AND NON-INSECT PESTS THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 2019-07-25 WO disclosed
US-20190216084-A1 Compositions And Methods For Killing Insect And Non-Insect Pests THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE 2019-07-18 US disclosed
CN-102099358-B Compound with serotoninergic activity, process for preparing same and pharmaceutical composition comprising same ACRAF 2014-01-22 CN disclosed
EP-2326645-B9 COMPOUND WITH SEROTONINERGIC ACTIVITY, PROCESS FOR PREPARING IT AND PHARMACEUTICAL COMPOSITION COMPRISING IT ACRAF (IT) 2013-04-17 EP disclosed
EP-2326645-B1 COMPOUND WITH SEROTONINERGIC ACTIVITY, PROCESS FOR PREPARING IT AND PHARMACEUTICAL COMPOSITION COMPRISING IT ACRAF (IT) 2012-11-07 EP disclosed
US-20110160201-A1 COMPOUND WITH SEROTONINERGIC ACTIVITY, PROCESS FOR PREPARING IT AND PHARMACEUTICAL COMPOSITION COMPRISING IT AZIENDE CHIMI. RIUN. ANG. FRANC. A.C.R.A.F. S.p.A. (IT) 2011-06-30 US disclosed
CN-102099358-A Compound with serotoninergic activity, process for preparing same and pharmaceutical composition comprising same ACRAF 2011-06-15 CN disclosed
EP-2326645-A1 COMPOUND WITH SEROTONINERGIC ACTIVITY, PROCESS FOR PREPARING IT AND PHARMACEUTICAL COMPOSITION COMPRISING IT Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F. S.p.A. (IT) 2011-06-01 EP disclosed
WO-2010012611-A1 COMPOUND WITH SEROTONINERGIC ACTIVITY, PROCESS FOR PREPARING IT AND PHARMACEUTICAL COMPOSITION COMPRISING IT AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A. (IT) 2010-02-04 WO disclosed
US-20040192956-A1 Synthesis of 2-chloromethyl-6-methylbenzoic ester AVENTIS PHARMA DEUTSCHLAND GMBH (DE) 2004-09-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230371508-A1 COMPOSITIONS AND METHODS FOR KILLING INSECT AND NON-INSECT PESTS BRS3, L3MBTL3, F7 ALDH1A1 2593/4885LMNA 3238/4885TSHR 901/4885
US-11805776-B2 Compositions and methods for killing insect and non-insect pests BRS3, L3MBTL3, F7 ALDH1A1 2593/4885LMNA 3238/4885TSHR 901/4885
US-20110160201-A1 COMPOUND WITH SEROTONINERGIC ACTIVITY, PROCESS FOR PREPARING IT AND PHARMACEUTICAL COMPOSITION COMPRISING IT TPH1, TPH2, HTR1A ALDH1A1 871/4885LMNA 3321/4885TSHR 906/4885
US-20190216084-A1 Compositions And Methods For Killing Insect And Non-Insect Pests BRS3, L3MBTL3, F7 ALDH1A1 2593/4885LMNA 3238/4885TSHR 901/4885
US-20220183287-A1 METHODS FOR KILLING PESTS L3MBTL3, AOC3, L3MBTL4 ALDH1A1 884/4885LMNA 3045/4885TSHR 3168/4885
US-20040192956-A1 Synthesis of 2-chloromethyl-6-methylbenzoic ester PPARA, PPARG, PPARD ALDH1A1 355/4885LMNA 2620/4885TSHR 574/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.